Phenanthridine derivatives as promising new anticancer agents: synthesis, biological evaluation and binding studies

I Azad, R Ahmad, T Khan, M Saquib… - Future Medicinal …, 2020 - Taylor & Francis
Aim: Phenanthridines are an essential class of nitrogenous heterocycles with extensive
applications in medicinal chemistry. The development of efficient and eco-friendly methods …

Investigation of salicylidene acylhydrazides derivatives: Molecular Docking, ADMET, and Molecular Dynamic Simulations were used in conjunction towards the design …

E Edache, A Uzairu, PA Mamza… - Turkish Computational …, 2022 - dergipark.org.tr
LysR-type transcription factor RovM is an important target of Yersinia pseudotuberculosis
drug discovery and the discovery of antibacterial is considered one of the greatest medical …

A Study on the Inhibitory Potential of Dpp-Iv Enzyme by Lobeline through In silico and In vivo Approaches

G Sabbagh, B Kurdi, W Khayata… - … Research Journal of …, 2021 - info.paperdigitallibrary.com
Aims: To evaluate the inhibitory activity of Lobeline natural alkaloid against dipeptidyl
peptidase IV (DPP IV) enzyme by in silico and in vivo experiments. Study Design: Evaluation …

Probing a lead inhibitor from the Thymus vulgaris against the Alzheimer protein: Human beta secretase

SR Kshirsagar, SI Shinde, M Hait - ES Materials & Manufacturing, 2023 - espublisher.com
Alzheimer's disease continues to be a focus of research due to the fact that it affects millions
of people worldwide as a result of the lack of effective therapeutic options. The primary goal …

[HTML][HTML] Molecular docking study on curcumin and its derivatives as inhibitors of BACE1 in the treatment of Alzheimer s disease

G Raghu, A Karunanithi, I Kannan - National Journal of Physiology …, 2018 - njppp.com
Background: Alzheimer s disease (AD) is a progressive neurodegenerative brain disorder,
and it is the main cause of dementia in the elderly. At present, no proper cure is available to …

[PDF][PDF] Protein-ligand docking study for the identification of plant-based ligands and their binding sites against Alzheimer's disease.

J Jafar, H Mudalige, O Perera - 2023 - bms.ac.lk
The presence of ApoE4 gene and the accumulation of beta-amyloid protein (Aβ) plaques in
the brain have been identified to cause Alzheimer's disease (AD). Current drugs used for AD …

In-silico interaction of antimalarial activity of secondary metabolic compounds Ginkgo biloba L. against wild type protein Plasmodium falciparum dihydrofolate …

S Sandy, IHS Sasto - AIP Conference Proceedings, 2022 - pubs.aip.org
Malaria, a parasitic disease caused by Plasmodium spp. and transmitted by the Anopheles
mosquito, remains one of the most common infectious diseases with high mortality and …

Applications of Molecular docking and virtual screening for Phytoconstituents to identify cognition enhancer activity

KN Meenakshi, M Sivakumar… - Research Journal of …, 2020 - indianjournals.com
The aim and objective of the present study to perform molecular docking studies for
phytoconstituents. The medicinal plant names are Ginko biloba, Acorus calamus …

[PDF][PDF] IN SILICO DOCKING ANALYSIS OF PHYTOCHEMICAL CONSTITUENTS FROM BARLERIA PRIONITIS

K Lavanya, K Rani, M Sravani - Journal For Innovative Development in …, 2024 - jidps.com
Alzheimer disease (AD) is a progressive neurodegenerative disease results in death of
brain cells. It causes memory loss and cognitive decline. The symptoms are mild at first and …