Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Dendrimers are a class of structurally defined macromolecules featured with a central core,
a low-density interior formed by repetitive branching units, and a high-density exterior …

Two new types of unsymmetrical bis (thiosemicarbazone) proligands and their neutral zinc
(II) and copper (II) complexes have been synthesized. These bifunctional ligands both …

Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

The possibility of selectively delivering metal complexes to a defined cohort of cells on the
basis of their metabolic features is a highly challenging goal, which may be extremely useful …

This article reviews Re and Tc organometallic chemistry and radiochemistry, focusing on the
most relevant aspects to design radiotools for molecular imaging and therapy. The review …

Increasing the potency of therapeutic compounds, while limiting side-effects, is a common
goal in medicinal chemistry. Ligands that effectively bind metal ions and also include …

This study describes the radiolabeling and preliminary biologic testing of
diethylenetriaminepentaacetic acid (DTPA)–deoxyglucose (DG) labeled with 99mTc. A one …

A series of nine organometallic technetium-99m and rhenium complexes of glucose are
presented and characterized in vitro regarding their potential as surrogates of [18F]-2-fluoro …

Three deoxyglucose (DG) derivatives, S-DG, MAG3-DG and MAMA-BA-DG, were
synthesized and labeled successfully with high labeling yields and high radio-chemical …