A panorama of sample preparation methods has been composed from 481 references, with
a highlight of some promising methods fast developed during recent years and a somewhat …

Covalent organic frameworks (COFs) is two-or three-dimensional crystalline porous
structures constructed by strong covalent bonds between organic subunits. As a new …

Sample preparation is a fundamental step in the proteomics workflow. However, it is not
easy to find compiled information updating this subject. In this paper, the strategies and …

A novel kind of immobilized trypsin reactor based on organic− inorganic hybrid silica
monoliths has been developed. With the presence of cetyltrimethyl ammonium bromide …

Microfluidic devices coupled to mass spectrometers have emerged as excellent tools for
solving the complex analytical challenges associated with the field of proteomics. Current …

With the acceleration of proteome research, increasing attention has been paid to
multidimensional liquid chromatography–mass spectrometry (MDLC–MS) due to its high …

Immobilized enzymatic reactors recently have drawn much attention because of the striking
advantages, such as high substrate turnover rate and ease in coupling with the separation …

Global proteomic analyses of complex protein samples in nanogram quantities require a
fastidious approach to achieve in-depth protein coverage and quantitative reproducibility …

Pepsin was immobilized on ethyl-bridged hybrid (BEH) particles, and digestion performance
was evaluated in a completely online format, with the specific intent of using the particles for …

Despite the developments for faster liquid chromatographic and mass spectral detection
techniques, the standard in-solution protein digestion for proteomic analyses has remained …