Advancing cell therapy for neurodegenerative diseases

S Temple - Cell stem cell, 2023 - cell.com
Cell-based therapies are being developed for various neurodegenerative diseases that
affect the central nervous system (CNS). Concomitantly, the roles of individual cell types in …

[HTML][HTML] Age-related macular degeneration: suitability of optogenetic therapy for geographic atrophy

GA Borchert, H Shamsnajafabadi, BWJ Ng… - Frontiers in …, 2024 - frontiersin.org
Age-related macular degeneration (AMD) is a growing public health concern given the
aging population and it is the leading cause of blindness in developed countries, affecting …

Retinal organoids in disease modeling and drug discovery: Opportunities and challenges

K Chakrabarty, D Nayak, J Debnath, D Das… - Survey of …, 2024 - Elsevier
Diseases leading to retinal cell loss can cause severe visual impairment and blindness. The
lack of effective therapies to address retinal cell loss and the absence of intrinsic …

[HTML][HTML] Application of organoid technology in the human health risk assessment of microplastics: A review of progresses and challenges

J Cong, J Wu, Y Fang, J Wang, X Kong, L Wang… - Environment …, 2024 - Elsevier
Microplastic (MP) pollution has become a global environmental issue, and increasing
concern has been raised about its impact on human health. Current studies on the toxic …

[HTML][HTML] Therapeutic landscape for inherited ocular diseases: Current and emerging therapies

HW Chan, J Oh, B Leroy - Singapore medical journal, 2023 - journals.lww.com
Inherited ocular diseases comprise a heterogeneous group of rare and complex diseases,
including inherited retinal diseases (IRDs) and inherited optic neuropathies. Recent success …

[HTML][HTML] Study on the Promotion of hADSCs Migration and Chemotaxis by SDF-1

C Jin, G Xu - The Asia-Pacific Journal of Ophthalmology, 2023 - journals.lww.com
Purpose: The purpose of this study was to investigate the chemotaxis effect of stromal cell-
derived factor-1 (SDF-1) on human adipose-derived stem cells (hADSCs). Methods: A …

Application of eye organoids in the study of eye diseases

S Ma, Y Xie, Q Wang, S Fu, H Wu - Experimental Eye Research, 2024 - Elsevier
The eyes are one of the most important sensory organs in the human body. Currently,
diseases such as limbal stem cell deficiency, cataract, retinitis pigmentosa and dry eye …

Advancing Vision Restoration — Stem Cell-Based Therapy for Retinal Diseases (Video)| JoVE

SBB Tun, E Shepherdson, HG Tay… - JoVE (Journal of Visualized …, 2023 - jove.com
Regeneration of photoreceptor cells using human pluripotent stem cells is a promising
therapy for the treatment of both hereditary and aging retinal diseases at advanced stages …

[HTML][HTML] Advances in Diagnosis and Therapy of Retinal Diseases

JB Jonas, DSC Lam - The Asia-Pacific Journal of Ophthalmology, 2023 - journals.lww.com
This issue of the Asia-Pacific Journal of Ophthalmology (APJO) includes a series of articles
on recent advances in the diagnosis and therapy of retinal diseases, written by leading …

[HTML][HTML] Regenerative Medicine, Advanced Stem Cell, and Gene Therapies for Eye Diseases

CJ Barnstable, JB Jonas, K Zhang - The Asia-Pacific Journal of …, 2022 - journals.lww.com
Ocular disorders are among the most prevalent diseases worldwide and rank highly in the
list of disability-associated life years as assessed in the Global Burden of Disease (GBD) …