309 Molecular role of dopamine in anhedonia linked to reward deficiency syndrome (RDS) and
anti- reward systems Mark S. Gold8, K Page 1 309 Molecular role of dopamine in anhedonia …

We have published extensively on the neurogenetics of brain reward systems with reference
to the genes related to dopaminergic function in particular. In 1996, we coined “Reward …

The C957T polymorphism of the human dopamine D2 receptor gene (DRD2) regulates
DRD2 availability in striatum in vivo. Specifically, the T allele predicts high DRD2 availability …

Drug‐related phenotypes are common complex and highly heritable traits. In the last few
years, candidate gene (CGAS) and genome‐wide association studies (GWAS) have …

Aims: Circadian clock genes are involved in the development of drug-induced behaviors
and regulate neurotransmission pathways in addiction. Our aim was to study whether …

The C957T (rs6277) single nucleotide polymorphism (SNP) of the human dopamine D2
receptor (DRD2) gene (DRD2) affects DRD2 mRNA stability and has been shown to predict …

During adolescence there is a significant increase in risk-taking behavior, including
experimenting with alcohol and drugs, which can lead to drug dependence. A new …

Abnormal behaviors involving dopaminergic gene polymorphisms often reflect an
insufficiency of usual feelings of satisfaction, or Reward Deficiency Syndrome (RDS). RDS …

Background: Children and adolescents, family history positive (FH+) for alcoholism, exhibit
differences in brain structure and functional activation when compared to family history …

The study aimed to explore in vivo the influence of cannabidiol (CBD) on the development of
alcohol tolerance in rats. Rats were treated with ethanol (3.0 g/kg, ip) and CBD (20 mg/kg …