The structural diversity and functional relevance of nucleic acids (NAs), mainly
deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are indispensable for almost all …

In this tutorial review, we focus on a multiscale method to compute the electronic absorption
line shape of molecular dyes embedded in a biological environment. To treat the coupling of …

We present a computational strategy to simulate the absorption lineshape of a molecule
embedded in a complex environment by using a polarizable QM/MM approach. This strategy …

A new set of cyanine-indole dyes was synthesized, characterized by optical and cytotoxic
properties and subsequently applied for live cell imaging. Furthermore, these dyes were …

Since their discovery, fluorescent probes have found widespread use in biological research.
Over time, multiple next-generation probes increased the fluorescence catalog by offering …

The nucleic acids staining ability of a series asymmetric monomeric monomethine cyanine
dyes prepared by simple and reliable synthetic procedure is demonstrated. The dyes show …

Observations of fluorescent cyanine dye behavior under illumination at 500 nm lead to a
novel concept in cell biology allowing the development of a new live cell assay called LUCS …

Cyanine dyes, as used in super‐resolution fluorescence microscopy, undergo light‐induced
“blinking”, enabling localization of fluorophores with spatial resolution beyond the optical …

Cyanine based chemosensing platforms have successfully been employed over the past
couple of decades in various fields of biomolecular sciences. Still a substantial number of …

The rational design of cyanine dyes for the fine-tuning of their photophysical properties
undoubtedly requires theoretical considerations for understanding and predicting their …