Cardiovascular disease (CVD) is the leading cause of mortality worldwide, accounting for
16.7 million deaths each year. The underlying cause of the majority of CVD is …

Experimental models of atherogenesis have provided a growing body of information about
molecular mechanisms of plaque growth; however, transition from coronary stability to …

Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive …

Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …

Calcific aortic valve disease (CAVD), and its clinical manifestation that is calcific aortic valve
stenosis, is the leading cause for valve disease within the developed world, with no current …

The idea that atherosclerosis is an inflammatory disease is no longer controversial. Instead,
much of the current research is now focused on understanding what drives this inflammation …

Far from being merely a passive cholesterol accumulation within the arterial wall, the
development of atherosclerosis is currently known to imply both inflammation and immune …

Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human
Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes …

The occurrence of stroke in populations is incompletely explained by traditional vascular risk
factors. Data from several case–control studies and one large study using case series …

Background T cell mediated inflammation contributes to atherogenesis and the onset of
acute cardiovascular disease. Effector T cell functions are under a tight control of a …