Lupus nephritis: new progress in diagnosis and treatment

C Yu, P Li, X Dang, X Zhang, Y Mao, X Chen - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …

Autoantibodies in systemic lupus erythematosus: From immunopathology to therapeutic target

H Lou, GS Ling, X Cao - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple
organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies …

Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity

J Suurmond, B Diamond - The Journal of clinical …, 2015 - Am Soc Clin Investig
In this Review we focus on the initiation of autoantibody production and autoantibody
pathogenicity, with a special emphasis on the targeted antigens. Release of intracellular …

In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis

A Chang, SG Henderson, D Brandt, N Liu… - The journal of …, 2011 - journals.aai.org
The most prevalent severe manifestation of systemic lupus erythematosus is nephritis, which
is characterized by immune complex deposition, inflammation, and scarring in glomeruli and …

Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis

P Mistry, MJ Kaplan - Clinical Immunology, 2017 - Elsevier
Nephritis is one of the most severe complications of systemic lupus erythematosus (SLE).
One key characteristic of lupus nephritis (LN) is the deposition of immune complexes …

Lupus nephritis: a critical review

AT Borchers, N Leibushor, SM Naguwa… - Autoimmunity …, 2012 - Elsevier
Lupus nephritis remains one of the most severe manifestations of systemic lupus
erythematosus associated with considerable morbidity and mortality. A better understanding …

Programmed cell death pathways in the pathogenesis of systemic lupus erythematosus

F Yang, Y He, Z Zhai, E Sun - Journal of immunology research, 2019 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease
characterized by excessive inflammatory and immune responses and tissue damage …

Biomarkers for lupus nephritis: a critical appraisal

CC Mok - BioMed Research International, 2010 - Wiley Online Library
Kidney disease is one of the most serious manifestations of systemic lupus erythematosus
(SLE). Despite the improvement in the medical care of SLE in the past two decades, the …

[HTML][HTML] Membranous nephropathy: recent travels and new roads ahead

LH Beck Jr, DJ Salant - Kidney international, 2010 - Elsevier
Insights from experimental studies have been recently translated into substantial advances
in understanding the pathogenesis of human membranous nephropathy (MN). These …

Emerging and critical issues in the pathogenesis of lupus

M Gatto, M Zen, A Ghirardello, S Bettio, N Bassi… - Autoimmunity …, 2013 - Elsevier
Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease,
encompassing either mild or severe manifestations. SLE was originally labeled as being an …