Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …

The stem cell-based therapy has emerged as a promising therapeutic strategy for treating
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However …

miRWalk is an open-source platform providing an intuitive interface that generates predicted
and validated miRNA-binding sites of known genes of human, mouse, rat, dog and cow. The …

Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and
development in bladder cancer. However, the underlying molecular mechanisms remain …

Abstract Background Circular RNAs (circRNAs) have received increasing attention in human
tumor research. However, there are still a large number of unknown circRNAs that need to …

The hepatic low-density lipoprotein receptor (LDLR) pathway is essential for clearing
circulating LDL cholesterol (LDL-C). Whereas the transcriptional regulation of LDLR is well …

Background Ulcerative colitis (UC) is an inflammatory disease of the intestinal mucosa, and
its incidence is steadily increasing worldwide. Intestinal immune dysfunction has been …

Despite advances in surgical technique and postoperative care, fibrosis remains the major
impediment to a marked reduction of intraocular pressure without the need of additional …

Exosomes are paracrine regulators of the tumor microenvironment and contain complex
cargo. We previously reported that exosomes released from acute myeloid leukemia (AML) …

Objective Accumulating evidence supports a role for exosomes in immune regulation. In this
study, we investigated the total circulating exosome transcriptome in relapsing–remitting …