[HTML][HTML] Native feedstock options for the polyhydroxyalkanoate industry in Europe: A review

B Gutschmann, B Huang, L Santolin, I Thiele… - Microbiological …, 2022 - Elsevier
Abstract The United Nations defined 17 Sustainable Development Goals (SDGs) in 2016
and agreed on fighting to confront the climate change and protecting the oceans and forests …

Synthetic biology toolkit of Ralstonia eutropha (Cupriavidus necator)

L Santolin, SL Riedel, CJ Brigham - Applied Microbiology and …, 2024 - Springer
Synthetic biology encompasses many kinds of ideas and techniques with the common
theme of creating something novel. The industrially relevant microorganism, Ralstonia …

Continuous feeding strategy for polyhydroxyalkanoate production from solid waste animal fat at laboratory‐and pilot‐scale

B Gutschmann, M Maldonado Simões… - Microbial …, 2023 - Wiley Online Library
Bioconversion of waste animal fat (WAF) to polyhydroxyalkanoates (PHAs) is an approach to
lower the production costs of these plastic alternatives. However, the solid nature of WAF …

[HTML][HTML] Metabolomics-based development of bioproduction processes toward industrial-scale production

K Tanaka, T Bamba, A Kondo, T Hasunuma - Current Opinion in …, 2024 - Elsevier
Highlights•Metabolomics accelerates bioproduction via strain, culture, and model
improvement.•Metabolomics is a powerful driving force for the DBTL-based strain …

Tailoring the HHx monomer content of P(HB-co-HHx) by flexible substrate compositions: scale-up from deep-well-plates to laboratory bioreactor cultivations

L Santolin, I Thiele, P Neubauer… - … in Bioengineering and …, 2023 - frontiersin.org
The enhanced material properties exhibited by the microbially synthetized
polyhydroxyalkanoate (PHA) copolymer poly (hydroxybutyrate-co-hydroxyhexanoate)[P (HB …

Medium-chain-length fatty acid catabolism in Cupriavidus necator H16: Transcriptome sequencing reveals differences from long-chain-length fatty acid β-oxidation …

CS Strittmatter, A Poehlein, A Himmelbach… - Applied and …, 2023 - Am Soc Microbiol
The number of genes encoding β-oxidation enzymes in Cupriavidus necator H16 (synonym,
Ralstonia eutropha H16) is high, but only the operons A0459-A0464 and A1526-A1531 …

Construction and application of petroleum-degrading bacterial agents: Community composition, lyophilization technology, and degradation mechanism

J Jing, T Wang, X Guo, P Huang, C Li, Y Qu - Journal of Environmental …, 2024 - Elsevier
The use of petroleum-degrading bacterial agents for environmental remediation presents
challenges primarily attributed to the restricted degradation capabilities of individual strains …

Polyhydroxyalkanoate production from animal by‐products: Development of a pneumatic feeding system for solid fat/protein‐emulsions

B Gutschmann, TH Högl, B Huang… - Microbial …, 2023 - Wiley Online Library
Fat‐containing animal by‐product streams are locally available in large quantities.
Depending on their quality, they can be inexpensive substrates for biotechnological …

[HTML][HTML] Solvent-free extraction of polyhydroxyalkanoates from wet biomass using mechanical cell disruption

I Thiele, M Gläser, C Pérez, T Grimm… - Separation and …, 2025 - Elsevier
Polyhydroxyalkanoates (PHAs) have great potential as bio-based and biodegradable
alternatives to fossil-based plastics. Despite many efforts to optimize the production process …

Mining robust in situ phosphorus-accumulating organisms via single-cell RACS-Culture for rational ecosystem engineering

J Xu, J Xiaoyan, H Pan, Y Gong, Y Ren, L Wang, R Mu… - 2024 - researchsquare.com
Rational engineering of ecosystems is often hindered by the inability to rapidly identify,
profile, culture and apply the microbes that underlie target metabolic activity in situ. Here, we …