The Janus (dual) model of immunoglobulin isotype evolution: Conservation and plasticity are the defining paradigms
MF Flajnik - Immunological Reviews, 2024 - Wiley Online Library
The study of antibodies in jawed vertebrates (gnathostomes) provides every immunologist
with a bird's eye view of how human immunoglobulins (Igs) came into existence and …
with a bird's eye view of how human immunoglobulins (Igs) came into existence and …
Towards a structural and functional analysis of the immunoglobulin-fold proteome
C Tawfeeq, J Song, U Khaniya, T Madej, J Wang… - Advances in Protein …, 2024 - Elsevier
The immunoglobulin fold (Ig fold) domain is a super-secondary structural motif consisting of
a sandwich with two layers of β-sheets that is present in many proteins with very diverse …
a sandwich with two layers of β-sheets that is present in many proteins with very diverse …
Understanding the biosynthesis of human IgM SAM-6 through a combinatorial expression of mutant subunits that affect product assembly and secretion
H Hasegawa, S Wang, E Kast, HT Chou, M Kaur… - Plos one, 2024 - journals.plos.org
Polymeric IgMs are secreted from plasma cells abundantly despite their structural complexity
and intricate multimerization steps. To gain insights into IgM's assembly mechanics that …
and intricate multimerization steps. To gain insights into IgM's assembly mechanics that …