[HTML][HTML] The immunologic role of IL-17 in psoriasis and psoriatic arthritis pathogenesis

A Blauvelt, A Chiricozzi - Clinical reviews in allergy & immunology, 2018 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven
by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17 …

IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa

JM Fletcher, B Moran, A Petrasca… - Clinical & Experimental …, 2020 - academic.oup.com
The skin is one of the most important organs in the body, providing integrity and acting as a
barrier to exclude microbes, allergens and chemicals. However, chronic skin inflammation …

Antibodies to watch in 2018

H Kaplon, JM Reichert - MAbs, 2018 - Taylor & Francis
The pace of antibody therapeutics development accelerated in 2017, and this faster pace is
projected to continue through 2018. Notably, the annual number of antibody therapeutics …

A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 12‐week efficacy, safety and speed of response …

A Blauvelt, K Papp, A Gottlieb, A Jarell… - British journal of …, 2020 - academic.oup.com
Background Patients with psoriasis value rapid and complete skin clearance. No head‐to‐
head studies have focused on early responses to interleukin (IL)‐17 vs. IL‐23 inhibitors …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

[HTML][HTML] Exacerbation of psoriasis following COVID-19 vaccination: report from a single center

YW Huang, TF Tsai - Frontiers in medicine, 2021 - frontiersin.org
The temporal association had been reported between vaccination and exacerbation of
psoriasis, and episodes of psoriasis flare-up have recently been attributed to COVID-19 …

[HTML][HTML] Psoriasis: From pathogenesis to pharmacological and nano-technological-based therapeutics

RG Petit, A Cano, A Ortiz, M Espina, J Prat… - International journal of …, 2021 - mdpi.com
Research in the pathogenesis of inflammatory skin diseases, such as skin dermatitis and
psoriasis, has experienced some relevant breakthroughs in recent years. The understanding …

[HTML][HTML] Deucravacitinib in moderate to severe psoriasis: clinical and quality-of-life outcomes in a phase 2 trial

D Thaçi, B Strober, KB Gordon, P Foley… - Dermatology and …, 2022 - Springer
Introduction Deucravacitinib is an oral, selective tyrosine kinase 2 inhibitor that
demonstrated therapeutic benefit in a Phase 2 clinical trial of adults with moderate to severe …

[HTML][HTML] Annoying psoriasis and atopic dermatitis: a narrative review

WY Chen, SC Chen, SY Hsu, YA Lin, CM Shih… - International journal of …, 2022 - mdpi.com
Skin is an important organ that mainly functions as a barrier. Skin diseases can damage a
person's self-confidence and reduce their willingness to socialize, as well as their social …

Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis

AM McGinley, SC Edwards, M Raverdeau… - Journal of …, 2018 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …