As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

The skin serves as the primary interface between our body and the external environment
and acts as a barrier against entry of physical agents, chemicals, and microbes …

Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Background: Psoriasis is a common, chronic inflammatory skin disorder, which can
significantly impact quality of life. Despite major breakthroughs in our understanding of the …

Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …

Keratinocytes are continuously in contact with external stimuli and have the capacity to
produce several soluble mediators. Pathogen-associated molecular patterns (PAMPs) are …

Adult human bone marrow-derived mesenchymal stem cells (hMSCs) are under study as
therapeutic delivery agents that assist in the repair of damaged tissues. To achieve the …

Current research and development of antigens for vaccination often center on purified
recombinant proteins, viral subunits, synthetic oligopeptides or oligosaccharides, most of …

The epidermal growth factor (EGF) family comprises multiple mediators such as transforming
growth factor-α, amphiregulin, heparin binding-EGF, and epiregulin, which are crucially …

Orchestrating when and how the cutaneous innate immune system should respond to
commensal or pathogenic microbes is a critical function of the epithelium. The cutaneous …