Computational modeling of realistic cell membranes

SJ Marrink, V Corradi, PCT Souza, HI Ingolfsson… - Chemical …, 2019 - ACS Publications
Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Emerging diversity in lipid–protein interactions

V Corradi, BI Sejdiu, H Mesa-Galloso… - Chemical …, 2019 - ACS Publications
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Characterization of lipid–protein interactions and lipid-mediated modulation of membrane protein function through molecular simulation

MP Muller, T Jiang, C Sun, M Lihan, S Pant… - Chemical …, 2019 - ACS Publications
The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

[HTML][HTML] The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model

FM Goñi - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2014 - Elsevier
The fluid mosaic model of Singer and Nicolson (1972) is a commonly used representation of
the cell membrane structure and dynamics. However a number of features, the result of four …

When physics takes over: BAR proteins and membrane curvature

M Simunovic, GA Voth, A Callan-Jones… - Trends in cell …, 2015 - cell.com
Cell membranes become highly curved during membrane trafficking, cytokinesis, infection,
immune response, or cell motion. Bin/amphiphysin/Rvs (BAR) domain proteins with their …

The 2018 biomembrane curvature and remodeling roadmap

P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations

R Metzler, JH Jeon, AG Cherstvy - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Curving cells inside and out: roles of BAR domain proteins in membrane shaping and its cellular implications

M Simunovic, E Evergren… - Annual review of cell …, 2019 - annualreviews.org
Many cellular processes rely on precise and timely deformation of the cell membrane. While
many proteins participate in membrane reshaping and scission, usually in highly specialized …

Building endocytic pits without clathrin

L Johannes, RG Parton, P Bassereau… - Nature reviews Molecular …, 2015 - nature.com
How endocytic pits are built in clathrin-and caveolin-independent endocytosis still remains
poorly understood. Recent insight suggests that different forms of clathrin-independent …

Computational 'microscopy'of cellular membranes

HI Ingólfsson, C Arnarez, X Periole… - Journal of cell …, 2016 - journals.biologists.com
Computational 'microscopy'refers to the use of computational resources to simulate the
dynamics of a molecular system. Tuned to cell membranes, this computational …