Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

The in-vivo profiling of iron and myelin across cortical depths and underlying white matter
has important implications for advancing knowledge about their roles in brain development …

Background Multiple sclerosis (MS) lesion evolution may involve changes in diamagnetic
myelin and paramagnetic iron. Conventional quantitative susceptibility mapping (QSM) can …

To separate the contributions of paramagnetic and diamagnetic sources within a voxel, a
magnetic susceptibility source separation method based solely on gradient-echo data has …

Purpose This study aimed to evaluate the potential of 3D EPI for improving the reliability of T
2* T _2^ ∗‐weighted data and quantification of R 2* R _2^ ∗ decay rate and susceptibility …

Although the past decade has seen remarkable progress in the evaluation and management
of multiple sclerosis (MS) and its mimics, many diagnostic, prognostic, and treatment …

Background and purpose The objective is to demonstrate feasibility of quantitative
susceptibility mapping (QSM) in autosomal dominant polycystic kidney disease (ADPKD) …

Susceptibility source separation, or χ‐separation, estimates diamagnetic (χdia) and
paramagnetic susceptibility (χpara) signals in the brain using local field and R2′(= R2 …

In MRI, researchers have long endeavored to effectively visualize myelin distribution in the
brain, a pursuit with significant implications for both scientific research and clinical …