New era of artificial intelligence and machine learning-based detection, diagnosis, and therapeutics in Parkinson's disease

R Gupta, S Kumari, A Senapati, RK Ambasta… - Ageing research …, 2023 - Elsevier
Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …

Exploring the frontiers of neuroimaging: a review of recent advances in understanding brain functioning and disorders

C Yen, CL Lin, MC Chiang - Life, 2023 - mdpi.com
Neuroimaging has revolutionized our understanding of brain function and has become an
essential tool for researchers studying neurological disorders. Functional magnetic …

Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson's disease

W Jiang, Q Li, R Zhang, J Li, Q Lin, J Li, X Zhou… - Nature …, 2023 - nature.com
Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of
Parkinson's disease (PD) treatment. However, there are significant gaps in our …

[HTML][HTML] Lead-DBS v3. 0: Mapping deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Functional neuroimaging as a catalyst for integrated neuroscience

ES Finn, RA Poldrack, JM Shine - Nature, 2023 - nature.com
Functional magnetic resonance imaging (fMRI) enables non-invasive access to the awake,
behaving human brain. By tracking whole-brain signals across a diverse range of cognitive …

Sleep and circadian rhythms in Parkinson's disease and preclinical models

J Hunt, EJ Coulson, R Rajnarayanan, H Oster… - Molecular …, 2022 - Springer
The use of animals as models of human physiology is, and has been for many years, an
indispensable tool for understanding the mechanisms of human disease. In Parkinson's …

Molecular imaging nanoprobes for theranostic applications

H He, X Zhang, L Du, M Ye, Y Lu, J Xue, J Wu… - Advanced Drug Delivery …, 2022 - Elsevier
As a non-invasive imaging monitoring method, molecular imaging can provide the location
and expression level of disease signature biomolecules in vivo, leading to early diagnosis of …

Novel nested patch-based feature extraction model for automated Parkinson's Disease symptom classification using MRI images

E Kaplan, E Altunisik, YE Firat, PD Barua… - Computer Methods and …, 2022 - Elsevier
Objective Parkinson's disease (PD) is a common neurological disorder with variable clinical
manifestations and magnetic resonance imaging (MRI) findings. We propose a handcrafted …

An enhanced multi-modal brain graph network for classifying neuropsychiatric disorders

L Liu, YP Wang, Y Wang, P Zhang, S Xiong - Medical image analysis, 2022 - Elsevier
It has been proven that neuropsychiatric disorders (NDs) can be associated with both
structures and functions of brain regions. Thus, data about structures and functions could be …

Implantable pulse generators for deep brain stimulation: challenges, complications, and strategies for practicality and longevity

C Sarica, C Iorio-Morin, DH Aguirre-Padilla… - Frontiers in Human …, 2021 - frontiersin.org
Deep brain stimulation (DBS) represents an important treatment modality for movement
disorders and other circuitopathies. Despite their miniaturization and increasing …