There is increasing evidence for an association between periodontitis/tooth loss and oral,
gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by …

Periodontitis is a disease characterized by tooth‐associated microbial biofilms that drive
chronic inflammation and destruction of periodontal‐supporting tissues. In some individuals …

Epigenetic mechanisms, namely DNA and histone modifications, are critical regulators of
immunity and inflammation which have emerged as potential targets for immunomodulating …

Gene expression is epigenetically regulated through DNA methylation and covalent
chromatin modifications, such as acetylation, phosphorylation, ubiquitination, sumoylation …

Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between
commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in …

The immune response to oral bacteria and the subsequent activation of inflammatory
signaling is not only dependent on genetic factors. The importance of so‐called epigenetic …

Periodontitis is a chronic oral inflammatory disease produced by bacteria. Gingival retraction
and bone and connective tissues resorption are the hallmarks of this disease. Chronic …

Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement
cascade of innate immunity have been suggested to play a key role in Alzheimer's disease …

Epigenetics describes chemical modifications of the genome that do not alter DNA
sequence but participate in the regulation of gene expression and cellular processes such …

Background The aim of this study was to investigate the association between periodontitis
and four single nucleotide polymorphisms (SNPs) in genes involved in epigenetic regulation …