[HTML][HTML] Evolution of norovirus
PA White - Clinical Microbiology and Infection, 2014 - Elsevier
Norovirus (NoV) is now the dominant aetiological agent of acute gastroenteritis, and, with
the recent introduction of rotavirus vaccines in many countries, this is likely to remain the …
the recent introduction of rotavirus vaccines in many countries, this is likely to remain the …
Norovirus antivirals: Where are we now?
NE Netzler, D Enosi Tuipulotu… - Medicinal research …, 2019 - Wiley Online Library
Human noroviruses inflict a significant health burden on society and are responsible for
approximately 699 million infections and over 200 000 estimated deaths worldwide each …
approximately 699 million infections and over 200 000 estimated deaths worldwide each …
Inhibitors of the hepatitis C virus polymerase; mode of action and resistance
The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and
economic burden in both developing and developed countries. Controlling the spread of …
economic burden in both developing and developed countries. Controlling the spread of …
Structure (s), function (s), and inhibition of the RNA-dependent RNA polymerase of noroviruses
Noroviruses belong to the Caliciviridae family of single-stranded positive-sense RNA
viruses. The genus Norovirus includes seven genogroups (designated GI-GVII), of which GI …
viruses. The genus Norovirus includes seven genogroups (designated GI-GVII), of which GI …
RNA-dependent RNA polymerases of picornaviruses: from the structure to regulatory mechanisms
C Ferrer-Orta, D Ferrero, N Verdaguer - Viruses, 2015 - mdpi.com
RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure
genome replication within the infected cells. RdRP function is critical not only for the virus life …
genome replication within the infected cells. RdRP function is critical not only for the virus life …
Calicivirus RNA-dependent RNA polymerases: evolution, structure, protein dynamics, and function
The Caliciviridae are viruses with a positive-sense, single-stranded RNA genome that is
packaged into an icosahedral, environmentally stable protein capsid. The family contains …
packaged into an icosahedral, environmentally stable protein capsid. The family contains …
Antiviral candidates for treating hepatitis E virus infection
NE Netzler, D Enosi Tuipulotu… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Globally, hepatitis E virus (HEV) causes significant morbidity and mortality each year.
Despite this burden, there are no specific antivirals available to treat HEV patients, and the …
Despite this burden, there are no specific antivirals available to treat HEV patients, and the …
Nucleocytoplasmic shuttling of the West Nile virus RNA‐dependent RNA polymerase NS5 is critical to infection
West Nile virus (WNV) is a single‐stranded, positive sense RNA virus of the family
Flaviviridae and is a significant pathogen of global medical importance. Flavivirus replication …
Flaviviridae and is a significant pathogen of global medical importance. Flavivirus replication …
Current and future antiviral strategies to tackle gastrointestinal viral infections
N Santos-Ferreira, J Van Dycke, J Neyts… - Microorganisms, 2021 - mdpi.com
Acute gastroenteritis caused by virus has a major impact on public health worldwide in terms
of morbidity, mortality, and economic burden. The main culprits are rotaviruses, noroviruses …
of morbidity, mortality, and economic burden. The main culprits are rotaviruses, noroviruses …
Targeting the viral polymerase of diarrhea-causing viruses as a strategy to develop a single broad-spectrum antiviral therapy
Viral gastroenteritis is an important cause of morbidity and mortality worldwide, being
particularly severe for children under the age of five. The most common viral agents of …
particularly severe for children under the age of five. The most common viral agents of …