Molecular population genetics
S Casillas, A Barbadilla - Genetics, 2017 - academic.oup.com
Molecular population genetics aims to explain genetic variation and molecular evolution
from population genetics principles. The field was born 50 years ago with the first measures …
from population genetics principles. The field was born 50 years ago with the first measures …
The power of natural variation for model organism biology
Genetic background effects have long been recognized and, in some cases studied, but they
are often viewed as a nuisance by molecular biologists. We suggest that genetic variation …
are often viewed as a nuisance by molecular biologists. We suggest that genetic variation …
Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila
MA Hanson, L Grollmus, B Lemaitre - Science, 2023 - science.org
Antimicrobial peptides are host-encoded immune effectors that combat pathogens and
shape the microbiome in plants and animals. However, little is known about how the host …
shape the microbiome in plants and animals. However, little is known about how the host …
Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits
It has been hypothesized that individually-rare hidden structural variants (SVs) could
account for a significant fraction of variation in complex traits. Here we identified more than …
account for a significant fraction of variation in complex traits. Here we identified more than …
Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population
GR Keele - G3: Genes, Genomes, Genetics, 2023 - academic.oup.com
Multiparental populations (MPPs) encompass greater genetic diversity than traditional
experimental crosses of two inbred strains, enabling broader surveys of genetic variation …
experimental crosses of two inbred strains, enabling broader surveys of genetic variation …
Mapping of resistance to corn borers in a MAGIC population of maize
Background Corn borers constitute an important pest of maize around the world; in particular
Sesamia nonagrioides Lefèbvre, named Mediterranean corn borer (MCB), causes important …
Sesamia nonagrioides Lefèbvre, named Mediterranean corn borer (MCB), causes important …
Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel
Using a new experimentally evolved multiparent mapping resource for C. elegans, Noble et
al. have outlined the genetic architecture of worm fertility.. Understanding the genetic basis …
al. have outlined the genetic architecture of worm fertility.. Understanding the genetic basis …
Evolution of reproductive behavior
Behaviors associated with reproduction are major contributors to the evolutionary success of
organisms and are subject to many evolutionary forces, including natural and sexual …
organisms and are subject to many evolutionary forces, including natural and sexual …
Host-pathogen coevolution increases genetic variation in susceptibility to infection
It is common to find considerable genetic variation in susceptibility to infection in natural
populations. We have investigated whether natural selection increases this variation by …
populations. We have investigated whether natural selection increases this variation by …
Polygenic adaptation to an environmental shift: temporal dynamics of variation under Gaussian stabilizing selection and additive effects on a single trait
KR Thornton - Genetics, 2019 - academic.oup.com
Predictions about the effect of natural selection on patterns of linked neutral variation are
largely based on models involving the rapid fixation of unconditionally beneficial mutations …
largely based on models involving the rapid fixation of unconditionally beneficial mutations …