[HTML][HTML] Advances in CRISPR therapeutics
The clustered regularly interspaced short palindromic repeats (CRISPR) renaissance was
catalysed by the discovery that RNA-guided prokaryotic CRISPR-associated (Cas) proteins …
catalysed by the discovery that RNA-guided prokaryotic CRISPR-associated (Cas) proteins …
Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
Neutrophil extracellular traps and its implications in inflammation: an overview
V Delgado-Rizo, MA Martínez-Guzmán… - Frontiers in …, 2017 - frontiersin.org
In addition to physical barriers, neutrophils are considered a part of the first line of immune
defense. They can be found in the bloodstream, with a lifespan of 6–8 h, and in tissue …
defense. They can be found in the bloodstream, with a lifespan of 6–8 h, and in tissue …
CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery
Genome editing offers promising solutions to genetic disorders by editing DNA sequences
or modulating gene expression. The clustered regularly interspaced short palindromic …
or modulating gene expression. The clustered regularly interspaced short palindromic …
CRISPR/Cas9 editing of endogenous banana streak virus in the B genome of Musa spp. overcomes a major challenge in banana breeding
Presence of the integrated endogenous banana streak virus (eBSV) in the B genome of
plantain (AAB) is a major challenge for breeding and dissemination of hybrids. As the eBSV …
plantain (AAB) is a major challenge for breeding and dissemination of hybrids. As the eBSV …
Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing
Transient delivery of CRISPR‐based genome editing effectors is important to reduce off‐
target effects and immune responses. Recently extracellular vesicles (EVs) have been …
target effects and immune responses. Recently extracellular vesicles (EVs) have been …
Various aspects of a gene editing system—crispr–cas9
E Janik, M Niemcewicz, M Ceremuga… - International journal of …, 2020 - mdpi.com
The discovery of clustered, regularly interspaced short palindromic repeats (CRISPR) and
their cooperation with CRISPR-associated (Cas) genes is one of the greatest advances of …
their cooperation with CRISPR-associated (Cas) genes is one of the greatest advances of …
CRISPR/Cas gene therapy
B Zhang - Journal of cellular physiology, 2021 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated
enzyme (Cas) is a naturally occurring genome editing tool adopted from the prokaryotic …
enzyme (Cas) is a naturally occurring genome editing tool adopted from the prokaryotic …
[HTML][HTML] Sequential LASER ART and CRISPR treatments eliminate HIV-1 in a subset of infected humanized mice
Elimination of HIV-1 requires clearance and removal of integrated proviral DNA from
infected cells and tissues. Here, sequential long-acting slow-effective release antiviral …
infected cells and tissues. Here, sequential long-acting slow-effective release antiviral …
[HTML][HTML] In vivo excision of HIV-1 provirus by saCas9 and multiplex single-guide RNAs in animal models
CRISPR-associated protein 9 (Cas9)-mediated genome editing provides a promising cure
for HIV-1/AIDS; however, gene delivery efficiency in vivo remains an obstacle to overcome …
for HIV-1/AIDS; however, gene delivery efficiency in vivo remains an obstacle to overcome …