Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised …

T Kishimoto, K Hagi, S Kurokawa, JM Kane… - The Lancet …, 2021 - thelancet.com
Background Evidence of comparative benefits of long-acting injectable antipsychotics (LAIs)
versus oral antipsychotics for schizophrenia has been inconsistent across study designs …

Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology

TRE Barnes, R Drake, C Paton… - Journal of …, 2020 - journals.sagepub.com
These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

What is the risk‐benefit ratio of long‐term antipsychotic treatment in people with schizophrenia?

CU Correll, JM Rubio, JM Kane - World Psychiatry, 2018 - Wiley Online Library
The long‐term benefit‐to‐risk ratio of sustained antipsychotic treatment for schizophrenia
has recently been questioned. In this paper, we critically examine the literature on the long …

Effectiveness of long-acting injectable vs oral antipsychotics in patients with schizophrenia: a meta-analysis of prospective and retrospective cohort studies

T Kishimoto, K Hagi, M Nitta, S Leucht… - Schizophrenia …, 2018 - academic.oup.com
Compared with oral antipsychotics (OAPs), long-acting injectable antipsychotics (LAIs)
should improve medication adherence and reduce relapses in schizophrenia. However …

[HTML][HTML] Epidemiology of schizophrenia and its management over 8-years period using real-world data in Spain

A Orrico-Sánchez, M López-Lacort, C Muñoz-Quiles… - BMC psychiatry, 2020 - Springer
Abstract Background Real-World Data (RWD) studies provide important insights in disease
epidemiology, in real clinical populations, with long follow-up periods. The aim of the …

Smart design of patient-centric long-acting products: from preclinical to marketed pipeline trends and opportunities

C Bassand, A Villois, L Gianola, G Laue… - Expert opinion on …, 2022 - Taylor & Francis
Introduction We see a development in the field of long-acting products to serve patients with
chronic diseases by providing benefits in adherence, efficacy, and safety of the treatment …

A further consideration on long-acting injectable versus oral antipsychotics in the treatment of schizophrenia: a narrative review and critical appraisal

T Suzuki - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Many patients with schizophrenia exhibit difficulties in maintaining adherence
to oral antipsychotics, calling for more reliable drug delivery systems. Areas covered: While …

Is paliperidone palmitate more effective than other long-acting injectable antipsychotics?

R Patel, E Chesney, M Taylor, D Taylor… - Psychological …, 2018 - cambridge.org
BackgroundPaliperidone palmitate is one of the most widely prescribed long-acting
injectable (LAI) antipsychotics in the UK. However, it is relatively expensive and there are …

Efficacy and safety profile of paliperidone palmitate injections in the management of patients with schizophrenia: an evidence-based review

R Emsley, S Kilian - Neuropsychiatric disease and treatment, 2018 - Taylor & Francis
The course of schizophrenia is characterized by multiple relapses, incomplete remission of
symptoms, enduring cognitive deficits, and social and occupational functional impairments …

[PDF][PDF] Paliperidone palmitate: effectiveness, safety, and the use for treatment of schizophrenia

M Jarema, P Bieńkowski, J Heitzman… - Psychiatr …, 2017 - scholar.archive.org
The aim of the study was to summarize the efficacy and tolerability of paliperidone palmitate,
an atypical long-acting antipsychotic drug. Paliperidone is a 9-hydroxy metabolite of …