IMI prevention of myopia and its progression

JB Jonas, M Ang, P Cho… - … & visual science, 2021 - iovs.arvojournals.org
The prevalence of myopia has markedly increased in East and Southeast Asia, and
pathologic consequences of myopia, including myopic maculopathy and high myopia …

An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

Three-year clinical trial of low-concentration atropine for myopia progression (LAMP) study: continued versus washout: phase 3 report

JC Yam, XJ Zhang, Y Zhang, YM Wang, SM Tang, FF Li… - Ophthalmology, 2022 - Elsevier
Purpose (1) To compare the efficacy of continued and stopping treatment for 0.05%, 0.025%,
and 0.01% atropine during the third year.(2) To evaluate the efficacy of continued treatment …

Efficacy and safety of 0.01% and 0.02% atropine for the treatment of pediatric myopia progression over 3 years: a randomized clinical trial

K Zadnik, E Schulman, I Flitcroft, JS Fogt… - JAMA …, 2023 - jamanetwork.com
Importance The global prevalence of myopia is predicted to approach 50% by 2050,
increasing the risk of visual impairment later in life. No pharmacologic therapy is approved …

Safety and efficacy of low-dose atropine eyedrops for the treatment of myopia progression in Chinese children: a randomized clinical trial

S Wei, SM Li, W An, J Du, X Liang, Y Sun… - JAMA …, 2020 - jamanetwork.com
Importance Because studies have suggested that atropine might slow the progression of
myopia in children, randomized clinical trials are warranted to understand this potential …

Two-year clinical trial of the low-concentration atropine for myopia progression (LAMP) study: phase 2 report

JC Yam, FF Li, X Zhang, SM Tang, BHK Yip, KW Kam… - Ophthalmology, 2020 - Elsevier
Purpose To evaluate the efficacy and safety of 0.05%, 0.025%, and 0.01% atropine eye
drops over 2 years to determine which is the optimal concentration for longer-term myopia …

Control of myopia using diffusion optics spectacle lenses: 12-month results of a randomised controlled, efficacy and safety study (CYPRESS)

J Rappon, C Chung, G Young, C Hunt… - British Journal of …, 2023 - bjo.bmj.com
Background Mutations in the L/M cone opsin gene array cause abnormally high perceived
retinal contrast and the development of myopia. Environmental factors may also lead to high …

Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression

X Liu, L Jiang, M Ke, IA Sigal, J Chua… - Nature Biomedical …, 2023 - nature.com
In myopic eyes, pathological remodelling of collagen in the posterior sclera has mostly been
observed ex vivo. Here we report the development of triple-input polarization-sensitive …

Efficacy and safety of 0.01% atropine for prevention of childhood myopia in a 2-year randomized placebo-controlled study

O Hieda, T Hiraoka, T Fujikado, S Ishiko… - Japanese journal of …, 2021 - Springer
Purpose Atropine eye drops prevent the progression of myopia, but their use has not been
tested in the Japanese schoolchildren population. Here, we evaluate the efficacy and safety …

Age effect on treatment responses to 0.05%, 0.025%, and 0.01% atropine: low-concentration atropine for myopia progression study

FF Li, Y Zhang, X Zhang, BHK Yip, SM Tang, KW Kam… - Ophthalmology, 2021 - Elsevier
Purpose To investigate the effect of age at treatment and other factors on treatment response
to atropine in the Low-Concentration Atropine for Myopia Progression (LAMP) Study. Design …