Clostridium perfringens-Induced Necrotic Diseases: An Overview

Y Fu, T Alenezi, X Sun - Immuno, 2022 - mdpi.com
Clostridium perfringens, a prevalent Gram-positive bacterium, causes necrotic diseases
associated with abundant life loss and economic burdens of billions of USD. The …

Lactobacillus Mucosal Vaccine Vectors: Immune Responses against Bacterial and Viral Antigens

JS LeCureux, GA Dean - Msphere, 2018 - Am Soc Microbiol
Lactic acid bacteria (LAB) have been utilized since the 1990s for therapeutic heterologous
gene expression. The ability of LAB to elicit an immune response against expressed foreign …

Lactobacillus casei displaying Clostridium perfringens NetB antigen protects chickens against necrotic enteritis

MA Shamshirgaran, M Golchin… - Applied Microbiology and …, 2022 - Springer
Necrotic enteritis is a serious economical disease of poultry caused by Clostridium
perfringens. NetB toxin of Clostridium perfringens is considered the causative agent of …

Bioengineered probiotics: synthetic biology can provide live cell therapeutics for the treatment of foodborne diseases

KCP Cruz, LO Enekegho, DT Stuart - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The rising prevalence of antibiotic resistant microbial pathogens presents an ominous health
and economic challenge to modern society. The discovery and large-scale development of …

Evaluation the efficacy of oral immunization of broiler chickens with a recombinant Lactobacillus casei vaccine vector expressing the Carboxy-terminal fragment of α …

MA Shamshirgaran, M Golchin, M Salehi… - BMC Veterinary …, 2023 - Springer
Background Clostridium perfringens (C. perfringens) is a serious anaerobic enteric
pathogen causing necrotic enteritis (NE) in broiler chickens. Following the ban on antibiotics …

Oral vaccine against IPNV based on antibiotic-free resistance recombinant Lactobacillus casei expressing CK6-VP2 fusion protein

X Hua, Y Zhou, Y Feng, K Duan, X Ren, J Sun, S Gao… - Aquaculture, 2021 - Elsevier
Infectious pancreatic necrosis (IPN) is a disease caused by the infectious pancreatic
necrosis virus (IPNV). The condition is associated with highly fatal hemorrhage and …

An atypical lipoteichoic acid from Clostridium perfringens elicits a broadly cross-reactive and protective immune response

CQ Wenzel, DC Mills, JM Dobruchowska… - Journal of Biological …, 2020 - ASBMB
Clostridium perfringens is a leading cause of food-poisoning and causes avian necrotic
enteritis, posing a significant problem to both the poultry industry and human health. No …

Necrotic enteritis in chickens: a comprehensive review of vaccine advancements over the last two decades

MA Shamshirgaran, M Golchin - Avian Pathology, 2025 - Taylor & Francis
Necrotic enteritis (NE) is a severe gastrointestinal disease that poses a significant threat to
poultry, leading to progressive deterioration of the small intestine, reduced performance, and …

Immunogenicity of a recombinant Lactobacillus casei, surface-expressed H151P mutant of Clostridium perfringens epsilon toxin and its protective responses in BALB …

M Alimolaei, M Golchin, A Baluch-Akbari - Toxicon, 2021 - Elsevier
Epsilon toxin (Etx) is the most important virulence factor of type D C. perfringens in
ruminants. The recombinant vaccines can be used against Etx intoxication. This study aimed …

Construction of an Integrated mCherry Red Fluorescent Protein Expression System for Labeling and Tracing in Lactiplantibacillus plantarum WCFS1

Y Yang, W Zhang, H Huan, W Xia, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Thorough intestinal adhesion and colonization greatly promote the probiotic properties of
lactic acid bacteria (LAB). Labeling and tracing with fluorescent proteins are effective and …