Genetics of glutamate and its receptors in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …
deficits in social interaction skills, impaired communication, and repetitive and restricted …
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics
AM Buch, C Liston - Neuropsychopharmacology, 2021 - nature.com
Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …
Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …
are not well understood. Using a large neuroimaging dataset, we identified three latent …
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes
Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal …
and higher-order cognitive processing. Connectome studies have suggested a principal …
A practical guide to linking brain-wide gene expression and neuroimaging data
The recent availability of comprehensive, brain-wide gene expression atlases such as the
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
Bridging the gap between connectome and transcriptome
The recent construction of brain-wide gene expression atlases, which measure the
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes
Schizophrenia has been conceived as a disorder of brain connectivity, but it is unclear how
this network phenotype is related to the underlying genetics. We used morphometric …
this network phenotype is related to the underlying genetics. We used morphometric …
Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder
KM Anderson, MA Collins, R Kong… - Proceedings of the …, 2020 - National Acad Sciences
Major depressive disorder emerges from the complex interactions of biological systems that
span genes and molecules through cells, networks, and behavior. Establishing how …
span genes and molecules through cells, networks, and behavior. Establishing how …
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
Neurodevelopmental disorders have a heritable component and are associated with region
specific alterations in brain anatomy. However, it is unclear how genetic risks for …
specific alterations in brain anatomy. However, it is unclear how genetic risks for …