The obesity pandemic, with its associated comorbidities of hypertension and diabetes,
constitutes a global public health issue. Importantly, there is an increasing prevalence of …

Background The mineralocorticoid receptor plays a significant role in the development of
chronic kidney disease (CKD) and associated cardiovascular complications. Classic …

The global burden of ischemic heart disease is burgeoning for both men and women.
Although advances have been made, the need for new sex-specific therapies targeting key …

Background: Galectin-3 is a biomarker that has been demonstrated to play a significant role
in myocardial fibrosis and remodeling in the pathogenesis of heart failure. Furthermore …

While obesity and its associated complications, mainly diabetes and hypertension, have
been the largest public health problems of modern world, the emerging data suggests an …

The broader implementation of albuminuria assessment in daily clinical practice facilitates
the identification of high-risk patients with early-stage CKD who are candidates for treatment …

The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is poorly
understood and therapeutic strategies are lacking. This study aimed to identify plasma …

Hypertensive heart disease (HHD) presents a substantial global health burden, spanning a
spectrum from subtle cardiac functional alterations to overt heart failure. In this …

Abstract Purpose of Review Finerenone is a novel, non-steroidal mineralocorticoid receptor
antagonist (MRAs) that has been investigated for the management of cardiorenal conditions …

The associations of left bundle branch block (LBBB) and right bundle branch block (RBBB)
with cardiovascular (CV) outcomes compared with normal QRS in heart failure patients with …