[HTML][HTML] The scientific case for brain simulations

GT Einevoll, A Destexhe, M Diesmann, S Grün, V Jirsa… - Neuron, 2019 - cell.com
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

Synaptic clustering and memory formation

G Kastellakis, P Poirazi - Frontiers in molecular neuroscience, 2019 - frontiersin.org
In the study of memory engrams, synaptic memory allocation is a newly emerged theme that
focuses on how specific synapses are engaged in the storage of a given memory …

Arbor—a morphologically-detailed neural network simulation library for contemporary high-performance computing architectures

N Abi Akar, B Cumming, V Karakasis… - 2019 27th euromicro …, 2019 - ieeexplore.ieee.org
We introduce Arbor, a performance portable library for simulation of large networks of multi-
compartment neurons on HPC systems. Arbor is open source software, developed under the …

[HTML][HTML] Reconstruction and simulation of a scaffold model of the cerebellar network

S Casali, E Marenzi, C Medini, C Casellato… - Frontiers in …, 2019 - frontiersin.org
Reconstructing neuronal microcircuits through computational models is fundamental to
simulate local neuronal dynamics. Here a scaffold model of the cerebellum has been …

IGF1-dependent synaptic plasticity of mitral cells in olfactory memory during social learning

Z Liu, Z Chen, C Shang, F Yan, Y Shi, J Zhang, B Qu… - Neuron, 2017 - cell.com
During social transmission of food preference (STFP), mice form long-term memory of food
odors presented by a social partner. How does the brain associate a social context with odor …

Principal cell activity induces spine relocation of adult-born interneurons in the olfactory bulb

V Breton-Provencher, K Bakhshetyan, D Hardy… - Nature …, 2016 - nature.com
Adult-born neurons adjust olfactory bulb (OB) network functioning in response to changing
environmental conditions by the formation, retraction and/or stabilization of new synaptic …

Parallel odor processing by mitral and middle tufted cells in the olfactory bulb

F Cavarretta, SD Burton, KM Igarashi, GM Shepherd… - Scientific Reports, 2018 - nature.com
The olfactory bulb (OB) transforms sensory input into spatially and temporally organized
patterns of activity in principal mitral (MC) and middle tufted (mTC) cells. Thus far, the …

Multi-scale spiking network model of human cerebral cortex

J Pronold, A van Meegen, RO Shimoura… - Cerebral …, 2024 - academic.oup.com
Although the structure of cortical networks provides the necessary substrate for their
neuronal activity, the structure alone does not suffice to understand the activity. Leveraging …

Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring

E Bernal-Meléndez, MC Lacroix, P Bouillaud… - Particle and Fibre …, 2019 - Springer
Background Airborne pollution, especially from diesel exhaust (DE), is known to have a
negative effect on the central nervous system in exposed human populations. However, the …

Scaling principles of distributed circuits

S Srinivasan, CF Stevens - Current Biology, 2019 - cell.com
Identifying shared quantitative features of a neural circuit across species is important for 3
reasons. Often expressed in the form of power laws and called scaling relationships [1, 2] …