How I treat high-risk multiple myeloma

E Zamagni, S Barbato, M Cavo - Blood, The Journal of the …, 2022 - ashpublications.org
Survival of multiple myeloma (MM) has significantly improved over the past decade;
however, a composed group of patients (15% to 20%), named high-risk (HR) MM, still …

Longer term outcomes with single‐agent belantamab mafodotin in patients with relapsed or refractory multiple myeloma: 13‐month follow‐up from the pivotal …

S Lonial, HC Lee, A Badros, S Trudel, AK Nooka… - Cancer, 2021 - Wiley Online Library
Background On the basis of the DREAMM‐2 study (ClinicalTrials. gov identifier
NCT03525678), single‐agent belantamab mafodotin (belamaf) was approved for patients …

[HTML][HTML] Efficacy of first-line treatment options in transplant-ineligible multiple myeloma: A network meta-analysis

S Kiss, N Gede, A Soos, P Hegyi, B Nagy… - Critical Reviews in …, 2021 - Elsevier
Background Despite major therapeutic advances, the rational choice of the most appropriate
first-line regimen in newly diagnosed transplant-ineligible multiple myeloma (TIE-MM) is …

Real-world effectiveness of ixazomib combined with lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: the REMIX study

M Macro, C Hulin, L Vincent, A Charvet-Rumpler… - Annals of …, 2023 - Springer
Ixazomib (IXA) is an oral proteasome inhibitor (PI) used in combination with lenalidomide
and dexamethasone (IXA-Rd) for patients with relapsed and/or refractory multiple myeloma …

Examining health related quality of life outcomes in multiple myeloma: past and future perspectives

G Hevroni, N Korde - Seminars in Oncology, 2022 - Elsevier
Multiple myeloma (MM) is a complex hematological malignancy. Advances in therapy over
the last decade have resulted in significant improvement in overall survival for patients with …

Low TYROBP expression predicts poor prognosis in multiple myeloma

H Luo, C Pan, L Wang, L Zheng, S Cao, X Hu… - Cancer Cell …, 2024 - Springer
Background Multiple myeloma (MM) is the second most common refractory hematologic
cancer. Searching for new targets and prognostic markers for MM is significant. Methods …

Trajectory, interactions, and predictors of higher symptom burden during induction therapy for multiple myeloma

M Kamal, Q Shi, SE Shen, C Cleeland… - Journal of Patient …, 2024 - Springer
Patients with multiple myeloma (MM) experience disabling symptoms that are difficult to
manage and may persist after induction therapy. Monitoring disease-related and induction …

Baseline lncRNA PCAT1 high expression and its longitude increment during induction therapy predict worse prognosis in multiple myeloma patients

P Zhao, X Zhao - Journal of Clinical Laboratory Analysis, 2021 - Wiley Online Library
Abstract Background Long noncoding RNA PCAT1 (lnc‐PCAT1) involves in the proliferation
and drug sensitivity of multiple myeloma (MM), while its prognostic role in MM patients is still …

Clinical consensus on treatments for transplant-ineligible newly diagnosed multiple myeloma: double-blinded Delphi panel

R Fonseca, A Rossi, R Medhekar, J Voelker… - Future …, 2024 - Taylor & Francis
Aim: Obtain clinical consensus on factors impacting first-line prescribing for transplant-
ineligible (TIE) patients with newly diagnosed multiple myeloma (NDMM). Materials & …

A real‐world retrospective–prospective analysis of efficacy and safety of combined ixazomib, lenalidomide, and dexamethasone in relapsed/refractory multiple …

A Furlan, M Cea, L Pavan, M Galli, C Clissa… - Cancer …, 2024 - Wiley Online Library
Introduction Ixazomib, lenalidomide, and dexamethasone (IRd) have been approved for the
treatment of relapsed/refractory multiple myeloma (RRMM) based on the results of the …