Bacteria‐induced epidemics and infectious diseases are seriously threatening the health of
people around the world. In addition, antibiotic therapy has been inducing increasingly more …

What is known and objective Meropenem, a carbapenem antibiotic, is widely prescribed for
the treatment of life‐threatening infections. The main parameter associated with its …

Twenty years ago, target concentration intervention (TCI) was distinguished from therapeutic
drug monitoring (TDM). It was proposed that TCI would bring more clinical benefit because …

Objectives Nephrotoxicity represents a major complication of vancomycin administration,
leading to high rates of morbidity and treatment failure. The aim of this meta-analysis was to …

Methicillin-resistant Staphylococcus aureus (MRSA) can cause harmful and potentially
deadly infections. Vancomycin remains the first-line antibiotic treatment for MRSA-derived …

Aims Vancomycin is an important antibiotic for critically ill patients with Gram‐positive
bacterial infections. Critically ill patients typically have severely altered pathophysiology …

Augmented renal clearance (ARC) can cause underexposure to vancomycin, thereby
increasing the risk of treatment failure. Our objective was to evaluate population …

Therapeutic drug monitoring (TDM) is a critical clinical tool used to optimize the safety and
effectiveness of drugs by measuring their concentration in biological fluids. These fluids are …

Vancomycin dosing should be accompanied by area under the concentration‐time curve
(AUC)–guided dosing using model‐informed precision dosing software according to the …

Background Vancomycin therapeutic drug monitoring (TDM) is based on achieving 24-h
area under the concentration–time curve to minimum inhibitory concentration cure …