Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …

Introduction: Pulmonary drug delivery is a complex field of research combining physics
which drive aerosol transport and deposition and biology which underpins efficacy and …

Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …

In silico methods can be used to estimate regional deposition of inhaled aerosols in regions
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …

Over the past years, advanced in vitro pulmonary platforms have witnessed exciting
developments that are pushing beyond traditional preclinical cell culture methods. Here, we …

This review covers the scope of multiscale computational fluid dynamics (CFD), laying the
framework for studying hydrodynamics with and without chemical reactions in single and …

The respiratory tract is an important route for beneficial drug aerosol or harmful particulate
matter to enter the body. To assess the therapeutic response or disease risk, whole-lung …

Large amounts of net electrical charge are known to accumulate on inhaled aerosols during
their generation using commonly-available inhalers. This effect often leads to superfluous …

The past decade has witnessed tremendous endeavors to deliver novel preclinical in vitro
lung models for pulmonary research endpoints, including foremost with the advent of organ …