The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Objectives To provide an overview of the clot viscoelastic testing technology and to describe
its utility in guiding blood product transfusions. Methods A case scenario will be discussed …

The neonatal hemostatic system is strikingly different from that of adults. Among other
differences, neonates exhibit hyporeactive platelets and decreased levels of coagulation …

Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic
maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo …

Background The small sample volume needed and the prompt availability of results make
viscoelastic methods like rotational thromboelastometry (ROTEM®) attractive for monitoring …

Thromboelastography (TEG) as a method of assessing global hemostatic and fibrinolytic
function has existed for more than 60 years. Improvements in TEG technology have led to …

Objective To systematically examine the evidence relating to the performance of rotational
viscoelastic testing in companion animals, to develop assay guidelines, and to identify …

Hemostasis is a dynamic age-related process, which gradually evolves from fetal life
throughout childhood until adulthood. Although at birth there is a hemostatic deficit of most …

Although the hemostatic potential of adult platelets has been investigated extensively,
regulation of platelet function during fetal life is less clear. Recent studies have provided …

The assessment of hemostatic disorders in neonates is crucial, but remains challenging for
clinicians. Although the concept of developmental hemostasis is widely accepted among …