Interindividual differences in caffeine metabolism and factors driving caffeine consumption

A Nehlig, SPH Alexander - Pharmacological reviews, 2018 - Elsevier
Most individuals adjust their caffeine intake according to the objective and subjective effects
induced by the methylxanthine. However, to reach the desired effects, the quantity of …

Chemical composition and health properties of coffee and coffee by-products

GV de Melo Pereira, DP de Carvalho Neto… - Advances in food and …, 2020 - Elsevier
Coffee can be an ally in the fight against diseases such as type 2 diabetes, cancer, hepatic
injury, cirrhosis, depression, suicidal behavior, and neurological and cardiovascular …

[HTML][HTML] Gene-by-environment interactions in Alzheimer's disease and Parkinson's disease

AR Dunn, KMS O'Connell, CC Kaczorowski - … & Biobehavioral Reviews, 2019 - Elsevier
Diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) arise from
complex interactions of genetic and environmental factors, with genetic variants regulating …

The effect of caffeine on the risk and progression of Parkinson's disease: A meta-analysis

CT Hong, L Chan, CH Bai - Nutrients, 2020 - mdpi.com
Coffee and caffeine are speculated to be associated with the reduced risk of Parkinson's
disease (PD). The present study aimed to investigate the disease-modifying potential of …

[PDF][PDF] Review on health benefit and risk of coffee consumption

HL Wachamo - Med. Aromat. Plants, 2017 - text2fa.ir
Coffee is the world's beloved drink that is the most regularly consumed caffeine-containing
beverage next to water and tea. It contains a multipart combination of chemicals …

Genes implicated in familial Parkinson's disease provide a dual picture of nigral dopaminergic neurodegeneration with mitochondria taking center stage

R Franco, R Rivas-Santisteban, G Navarro… - International journal of …, 2021 - mdpi.com
The mechanism of nigral dopaminergic neuronal degeneration in Parkinson's disease (PD)
is unknown. One of the pathological characteristics of the disease is the deposition of α …

[HTML][HTML] Caffeine: A Multifunctional Efficacious Molecule with Diverse Health Implications and Emerging Delivery Systems

X Song, M Singh, KE Lee, R Vinayagam… - International Journal of …, 2024 - mdpi.com
Natural caffeine is found in many plants, including coffee beans, cacao beans, and tea
leaves. Around the world, many beverages, including coffee, tea, energy drinks, and some …

An outlook on the role of decaffeinated coffee in neurodegenerative diseases

R Colombo, A Papetti - Critical Reviews in Food Science and …, 2020 - Taylor & Francis
Coffee is reported to be among the most widely consumed beverages in the world and
coffee consumption has been associated with reductions in the risk of several chronic …

Purinergic receptors in neurological diseases with motor symptoms: targets for therapy

Á Oliveira-Giacomelli, Y Naaldijk… - Frontiers in …, 2018 - frontiersin.org
Since proving adenosine triphosphate (ATP) functions as a neurotransmitter in neuron/glia
interactions, the purinergic system has been more intensely studied within the scope of the …

Single nucleotide polymorphisms associated with gut homeostasis influence risk and age-at-onset of Parkinson's disease

AM Gorecki, MC Bakeberg, F Theunissen… - Frontiers in aging …, 2020 - frontiersin.org
Research is increasingly focusing on gut inflammation as a contributor to Parkinson's
disease (PD). Such gut inflammation is proposed to arise from a complex interaction …