Beneficial health effects of glucosinolates-derived isothiocyanates on cardiovascular and neurodegenerative diseases

RM Kamal, AF Abdull Razis, NS Mohd Sukri… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …

Mechanisms underlying biological effects of cruciferous glucosinolate-derived isothiocyanates/indoles: a focus on metabolic syndrome

M Esteve - Frontiers in Nutrition, 2020 - frontiersin.org
An inverse correlation between vegetable consumption and the incidence of cancer has
long been described. This protective effect is stronger when cruciferous vegetables are …

Developing multifunctional crops by engineering Brassicaceae glucosinolate pathways

H Qin, GJ King, P Borpatragohain, J Zou - Plant communications, 2023 - cell.com
Glucosinolates (GSLs), found mainly in species of the Brassicaceae family, are one of the
most well-studied classes of secondary metabolites. Produced by the action of myrosinase …

Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α

F Hadrich, S Sayadi - Lipids in health and disease, 2018 - Springer
Background Apigetrin, a flavonoid found in many plant leaves and seeds, has been known
to possess antimutagenic, anti-cancer, antioxidant and anti-inflammatory properties. Here …

Essential oil components with antidiabetic and anti-obesity properties: a review of mechanisms of action and toxicity

E Ejiofor, S Oyedemi… - Journal of Essential …, 2023 - Taylor & Francis
Diabetes and obesity are critical health concerns in the world, characterized by weak insulin
secretion and activity, leading to increased blood glucose concentrations and an …

Inula britannica Inhibits Adipogenesis of 3T3-L1 Preadipocytes via Modulation of Mitotic Clonal Expansion Involving ERK 1/2 and Akt Signaling Pathways

HS Yu, WJ Kim, WY Bae, NK Lee, HD Paik - Nutrients, 2020 - mdpi.com
The flower of Inula britannica contains various phenolic compounds with prophylactic
properties. This study aimed to determine the anti-adipogenic effect of an I. britannica flower …

Improving the Health-Benefits of Kales (Brassica oleracea L. var. acephala DC) through the Application of Controlled Abiotic Stresses: A Review

E Ortega-Hernández, M Antunes-Ricardo… - Plants, 2021 - mdpi.com
Kale (Brassica oleracea L. var. acephala DC) is a popular cruciferous vegetable originating
from Central Asia, and is well known for its abundant bioactive compounds. This review …

Comparative evaluation of Brassica oleracea, Ocimum basilicum, and Moringa oleifera leaf extracts on lipase inhibition and adipogenesis in 3T3‐L1 adipocytes

I Nallamuthu, A Jain, T Anand - Journal of Food Biochemistry, 2022 - Wiley Online Library
The anti‐adipogenic effects of alcohol extract of Brassica oleracea (BO), Ocimum basilicum
(OB), and Moringa oleifera (MO) leaves on 3T3‐L1 pre‐adipocyte as well as their lipase …

Molecular targets in cancer prevention by 4-(methylthio) butyl isothiocyanate-A comprehensive review

D Singh, R Arora, A Bhatia, H Singh, B Singh, S Arora - Life sciences, 2020 - Elsevier
The consumption of cruciferous vegetables rich in isothiocyanates has long been associated
with a reduced risk of various types of cancer. 4-(methylthio) butyl isothiocyanate also called …

Bromophenol (5‐bromo‐3,4‐dihydroxybenzaldehyde) isolated from red alga Polysiphonia morrowii inhibits adipogenesis by regulating expression of adipogenic …

SC Ko, Y Ding, J Kim, BR Ye, EA Kim… - Phytotherapy …, 2019 - Wiley Online Library
The aim of the present study was to investigate the effect of 5‐bromo‐3, 4‐
dihydroxybenzaldehyde (BD) isolated from Polysiphonia morrowii on adipogenesis and …