[HTML][HTML] Farnesoid X receptor (FXR): Structures and ligands
L Jiang, H Zhang, D Xiao, H Wei, Y Chen - Computational and structural …, 2021 - Elsevier
Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly
expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved …
expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved …
Marine natural products
Covering: 2011. Previous review: Nat. Prod. Rep., 2012, 29, 144–222. This review covers
the literature published in 2011 for marine natural products, with 870 citations (558 for the …
the literature published in 2011 for marine natural products, with 870 citations (558 for the …
FXR signaling in the enterohepatic system
T Matsubara, F Li, FJ Gonzalez - Molecular and cellular endocrinology, 2013 - Elsevier
Enterohepatic circulation serves to capture bile acids and other steroid metabolites
produced in the liver and secreted to the intestine, for reabsorption back into the circulation …
produced in the liver and secreted to the intestine, for reabsorption back into the circulation …
Biological activities of meroterpenoids isolated from different sources
Meroterpenoids are natural products synthesized by unicellular organisms such as bacteria
and multicellular organisms such as fungi, plants, and animals, including those of marine …
and multicellular organisms such as fungi, plants, and animals, including those of marine …
Marine natural products
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …
literature published in 2002 for marine natural products, with 579 citations (413 for the …
[HTML][HTML] Meroterpenoids: A comprehensive update insight on structural diversity and biology
Meroterpenoids are secondary metabolites formed due to mixed biosynthetic pathways
which are produced in part from a terpenoid co-substrate. These mixed biosynthetically …
which are produced in part from a terpenoid co-substrate. These mixed biosynthetically …
New anticancer agents: recent developments in tumor therapy
Increasing recurrence of mammalian tumors and severe side-effects of chemotherapeutic
agents reduce the clinical efficacy of a large variety of anticancer agents that are currently …
agents reduce the clinical efficacy of a large variety of anticancer agents that are currently …
Algae-derived bioactive compounds with anti-lung cancer potential
Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung
cancer potential are of a great interest and considered as very promising alternative to …
cancer potential are of a great interest and considered as very promising alternative to …
[HTML][HTML] Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
V Hiebl, A Ladurner, S Latkolik, VM Dirsch - Biotechnology advances, 2018 - Elsevier
Nuclear receptors (NRs) represent attractive targets for the treatment of metabolic syndrome-
related diseases. In addition, natural products are an interesting pool of potential ligands …
related diseases. In addition, natural products are an interesting pool of potential ligands …
Natural products diversity of marine ascidians (Tunicates; Ascidiacea) and successful drugs in clinical development
SK Palanisamy, NM Rajendran, A Marino - Natural products and …, 2017 - Springer
This present study reviewed the chemical diversity of marine ascidians and their
pharmacological applications, challenges and recent developments in marine drug …
pharmacological applications, challenges and recent developments in marine drug …