[HTML][HTML] A chemical toolbox to unveil synthetic nature-inspired antifouling (NIAF) compounds

AR Neves, S Godinho, C Gonçalves, AS Gomes… - Marine Drugs, 2024 - mdpi.com
The current scenario of antifouling (AF) strategies to prevent the natural process of marine
biofouling is based in the use of antifouling paints containing different active ingredients …

[HTML][HTML] Potential of Marine Sponge Metabolites against Prions: Bromotyrosine Derivatives, a Family of Interest

M Sinane, C Grunberger, L Gentile, C Moriou… - Marine drugs, 2024 - mdpi.com
The screening of 166 extracts from tropical marine organisms (invertebrates, macroalgae)
and 3 cyclolipopeptides from microorganisms against yeast prions highlighted the potential …

Pharmacokinetics and Tissue Distribution of Itampolin A following Intragastric and Intravenous Administration in Rats Using Ultra-High-Performance Liquid …

Q Sun, J Liang, Q Zhang, X Wang, N Zhao, F Meng - Molecules, 2024 - mdpi.com
Itampolin A, a natural brominated tyrosine alkaloid isolated from the sponge Iotrochota
purpurea, has been shown to have good inhibitory effects in lung cancer cells as a p38α …

Nature‐inspired Novel Quaternary Ammonium Compounds: Synthesis, Antibacterial and Antibiofilm Activity

L Muzychka, D Hodyna, L Metelytsia, O Smolii - ChemMedChem - Wiley Online Library
Inspired by marine compounds isolated from sponges and the increased need for new
effective antimicrobials, novel quaternary ammonium compounds with long alkyl chains (C8 …