As hydration contributions to stability of macromolecular assemblies in aqueous solution,
hydrophobic effects are virtually universally acknowledged. Hydrophobic effects are widely …

Molecular dynamics simulations of biological membranes have come of age. Simulations of
pure lipid bilayers are extending our understanding of both optimal simulation procedures …

Peptide− membrane interactions are important for understanding the binding, partitioning,
and folding of membrane proteins; the activity of antimicrobial and fusion peptides; and a …

Tyrothricin, a complex mixture of antibiotic peptides from Bacillus brevis, was reported in
1944 to have antimalarial activity rivalling that of quinine in chickens infected with …

We have performed molecular dynamics simulations of peptide hormone bradykinin (BK)
and its fragment des-Arg9-BK in the presence of an anionic lipid bilayer, with an aim toward …

Six major tyrocidines, purified from the antibiotic tyrothricin complex produced by Bacillus
aneurinolyticus, showed significant lytic and growth inhibitory activity towards the Gram+ …

Alzheimer's disease (AD) is a significant contributor to cognitive decline and is responsible
for about half of the cases of dementia in later life. Although exact etiology of AD is not …

The structural properties of the endogenous opioid peptide dynorphin A (1–17)(DynA), a
potential analgesic, were studied with molecular dynamics simulations in …

The field of tissue engineering is poised to be positively influenced by the advent of
supramolecular biopolymers, because of their promising tailorability coming from the bottom …

The coupling of the constitutive expression for the electrostatic potential as specified through
Poisson's equation together with the constitutive equations for the mechanisms of …