[HTML][HTML] The functional role of lipoproteins in atherosclerosis: novel directions for diagnosis and targeting therapy

Y Lu, X Cui, L Zhang, X Wang, Y Xu, Z Qin… - Aging and …, 2022 - ncbi.nlm.nih.gov
Dyslipidemia, characterized by a high level of lipids (cholesterol, triglycerides, or both), can
increase the risk of developing and progressing atherosclerosis. As atherosclerosis …

Designing polymers with sugar-based advantages for bioactive delivery applications

Y Zhang, JW Chan, A Moretti, KE Uhrich - Journal of Controlled Release, 2015 - Elsevier
Sugar-based polymers have been extensively explored as a means to increase drug
delivery systems' biocompatibility and biodegradation. Here, we review the use of sugar …

Flash technology-based self-assembly in nanoformulation: Fabrication to biomedical applications

H Hu, C Yang, M Li, D Shao, HQ Mao, KW Leong - Materials Today, 2021 - Elsevier
Advances in nanoformulation have driven progress in biomedicine by producing nanoscale
tools for biosensing, imaging, and drug delivery. Flash-based technology, the combination of …

Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

DR Lewis, LK Petersen, AW York… - Proceedings of the …, 2015 - National Acad Sciences
Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial walls, is a focal trigger
of chronic coronary, intracranial, and peripheral arterial diseases, which together account for …

Recent advances in managing atherosclerosis via nanomedicine

CKW Chan, L Zhang, CK Cheng, H Yang, Y Huang… - Small, 2018 - Wiley Online Library
Atherosclerosis, driven by chronic inflammation of the arteries and lipid accumulation on the
blood vessel wall, underpins many cardiovascular diseases with high mortality rates …

SR-A-targeted phase-transition nanoparticles for the detection and treatment of atherosclerotic vulnerable plaques

M Ye, J Zhou, Y Zhong, J Xu, J Hou… - … applied materials & …, 2019 - ACS Publications
Atherosclerosis is a major cause of sudden death and myocardial infarction, instigated by
unstable plaques. Thus, the early detection of unstable plaques and corresponding …

Low-density lipoprotein nanomedicines: mechanisms of targeting, biology, and theranostic potential

L Di, A Maiseyeu - Drug Delivery, 2021 - Taylor & Francis
Native nanostructured lipoproteins such as low-and high-density lipoproteins (LDL and
HDL) are powerful tools for the targeted delivery of drugs and imaging agents. While the …

Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology–A new chance for causative therapy?

J Groner, A Goepferich, M Breunig - Journal of Controlled Release, 2021 - Elsevier
Atherosclerosis is the leading cause of death in developed countries. The pathogenetic
mechanism relies on a macrophage-based immune reaction to low density lipoprotein (LDL) …

Vascular‐targeted nanocarriers: design considerations and strategies for successful treatment of atherosclerosis and other vascular diseases

WJ Kelley, H Safari, G Lopez‐Cazares… - Wiley …, 2016 - Wiley Online Library
Vascular‐targeted nanocarriers are an attractive option for the treatment of a number of
cardiovascular diseases, as they allow for more specific delivery and increased efficacy of …

Nanotechnological approach to delivering nutraceuticals as promising drug candidates for the treatment of atherosclerosis

SC Pillai, A Borah, EM Jacob, DS Kumar - Drug Delivery, 2021 - Taylor & Francis
Atherosclerosis is Caesar's sword, which poses a huge risk to the present generation.
Understanding the atherosclerotic disease cycle would allow ensuring improved diagnosis …