Exercise training in chronic heart failure: improving skeletal muscle O2 transport and utilization

DM Hirai, TI Musch, DC Poole - American Journal of …, 2015 - journals.physiology.org
Chronic heart failure (CHF) impairs critical structural and functional components of the O2
transport pathway resulting in exercise intolerance and, consequently, reduced quality of …

[HTML][HTML] Impacts of exercise intervention on various diseases in rats

R Wang, H Tian, D Guo, Q Tian, T Yao… - Journal of Sport and Health …, 2020 - Elsevier
Background Exercise is considered as an important intervention for treatment and
prevention of several diseases, such as osteoarthritis, obesity, hypertension, and …

Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction

KL Weeks, X Gao, XJ Du, EJH Boey… - Circulation: Heart …, 2012 - Am Heart Assoc
Background—Numerous molecular and biochemical changes have been linked with the
cardioprotective effects of exercise, including increases in antioxidant enzymes, heat shock …

[HTML][HTML] MicroRNAs in heart and circulation during physical exercise

L Wang, Y Lv, G Li, J Xiao - Journal of sport and health science, 2018 - Elsevier
Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are
a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of …

Interaction between exercise and hypertension in spontaneously hypertensive rats: a meta-analysis of experimental studies

KD Schlüter, R Schreckenberg… - Hypertension …, 2010 - nature.com
The effect of exercise on the progression of hypertension and development of heart failure
has been extensively studied in spontaneously hypertensive rats (SHRs), but results …

[HTML][HTML] Long-term low intensity physical exercise attenuates heart failure development in aging spontaneously hypertensive rats

LU Pagan, RL Damatto, MDM Cezar… - Cellular physiology and …, 2015 - karger.com
Background: Physical exercise is a strategy to control hypertension and attenuate pressure
overload-induced cardiac remodeling. The influence of exercise on cardiac remodeling …

[HTML][HTML] Exercise-based cardiac rehabilitation improves hemodynamic responses after coronary artery bypass graft surgery

FE Ghashghaei, M Sadeghi, SM Marandi… - ARYA …, 2012 - ncbi.nlm.nih.gov
BACKGROUND: Cardiovascular disorders are an important public health problem
worldwide. They are also the leading cause of mortality and morbidity. Therefore, American …

Role of proinflammatory cytokines and redox homeostasis in exercise-induced delayed progression of hypertension in spontaneously hypertensive rats

D Agarwal, M Haque, S Sriramula, N Mariappan… - …, 2009 - Am Heart Assoc
Hypertension is a well-known risk factor for various cardiovascular diseases. Recently,
exercise has been recommended as a part of lifestyle modification for all hypertensive …

Beneficial effects of physical exercise on functional capacity and skeletal muscle oxidative stress in rats with aortic stenosis‐induced heart failure

MJ Gomes, PF Martinez, DHS Campos… - Oxidative medicine …, 2016 - Wiley Online Library
Objective. We evaluated the influence of exercise on functional capacity, cardiac
remodeling, and skeletal muscle oxidative stress, MAPK, and NF‐κB pathway in rats with …

Exercise training alters left ventricular geometry and attenuates heart failure in dahl salt-sensitive hypertensive rats

M Miyachi, H Yazawa, M Furukawa, K Tsuboi… - …, 2009 - Am Heart Assoc
The clinical efficacy of exercise training in individuals with heart failure is well established,
but the mechanism underlying such efficacy has remained unclear. An imbalance between …