Structural principles analysis of host-pathogen protein-protein interactions: A structural bioinformatics survey

H Chen, W Guo, J Shen, L Wang, J Song - Ieee Access, 2018 - ieeexplore.ieee.org
Computational-intelligence methods in bioinformatics and systems biology show promising
potential for leveraging abundant, large-scale molecular data. These methods can facilitate …

Leveraging stacked denoising autoencoder in prediction of pathogen-host protein-protein interactions

H Chen, J Shen, L Wang, J Song - 2017 IEEE International …, 2017 - ieeexplore.ieee.org
In big data research related to bioinformatics, one of the most critical areas is proteomics. In
this paper, we focus on the protein-protein interactions, especially on pathogen-host protein …

A framework towards data analytics on host–pathogen protein–protein interactions

H Chen, J Shen, L Wang, J Song - Journal of Ambient Intelligence and …, 2020 - Springer
With the rapid development of high-throughput technologies, systems biology is now
embracing a great opportunity made possible by the increased accumulation of data …

Leveraging SMOTE in a two-layer model for prediction of protein-protein interactions

H Chen, L Wang, CH Chi, J Shen - 2019 Seventh International …, 2019 - ieeexplore.ieee.org
The research of the mechanisms of infectious diseases between host and pathogens
remains a hot topic. It takes stock of the interactions data between host and pathogens …

APEX2S: A two‐layer machine learning model for discovery of host‐pathogen protein‐protein interactions on cloud‐based multiomics data

H Chen, J Shen, L Wang, CH Chi - … and Computation: Practice …, 2020 - Wiley Online Library
Presented by the avalanche of biological interactions data, computational biology is now
facing greater challenges on big data analysis and solicits more studies to mine and …

Towards elucidating the structural principles of host-pathogen protein-protein interaction networks: A bioinformatics survey

H Chen, J Song, G Sun, J Shen… - 2017 IEEE International …, 2017 - ieeexplore.ieee.org
The ultimate goal of systems biology research area is to accurately predict the behavior of
biological systems through the construction of computational models, using the related …

Research on F-OFDM subband filter algorithm for three major 5G application scenarios

Y Chen, Y Wang, H Wu - Proceedings of the 2020 4th International …, 2020 - dl.acm.org
With the proposal of three major 5G (5th generation wireless systems) application scenarios,
the first NR (New Radio) specification version of 3GPP (3rd Generation Partnership Project) …

Collaborative data analytics towards prediction on pathogen-host protein-protein interactions

H Chen, J Shen, L Wang, J Song - 2017 IEEE 21st International …, 2017 - ieeexplore.ieee.org
Nowadays more and more data are being sequenced and accumulated in system biology,
which brings the data analytics researchers to a brand new era, namelybig data', to extract …

Towards biological sequence data service with insights

H Chen, J Shen, L Wang, CH Chi - 2018 IEEE International …, 2018 - ieeexplore.ieee.org
Testable prediction outcomes generated by computational models based on available
databases are the primary sources helping to design biological experiments. Although …

Utilizing machine learning techniques to rapidly identify MUC2 expression in colon cancer tissues

PK Periyakoil - 2018 - thesis.library.caltech.edu
Colorectal cancer is the third-most common form of cancer among American men and
women. Like most tumors, colon cancer is sustained by a subpopulation of “stem cells” that …