Characterization of rodent Sertoli cell primary cultures
Sertoli cells play a vital role in spermatogenesis by offering physical and nutritional support
to the differentiating male germ cells. They form the blood–testis barrier and secrete growth …
to the differentiating male germ cells. They form the blood–testis barrier and secrete growth …
3-Monochloropropane-1, 2-diol causes irreversible damage to reproductive ability independent of hormone changes in adult male rats
HZ Xing, B Fang, GF Pang, FZ Ren - Food and Chemical Toxicology, 2019 - Elsevier
MCPD, a contaminant frequently detected in foodstuffs, has been reported to damage
human kidneys and testes. Previous studies can be used to evaluate the risk to humans of …
human kidneys and testes. Previous studies can be used to evaluate the risk to humans of …
The expanded roles of Sertoli cells: lessons from Sertoli cell ablation models
D Rebourcet, PJ O'Shaughnessy, LB Smith - Current Opinion in Endocrine …, 2019 - Elsevier
Abstract Since Enrico Sertoli's first depiction of Sertoli cells in the 19th century, the role of
Sertoli cells as a hub for both testis biology and as a potential therapeutic tool, continues to …
Sertoli cells as a hub for both testis biology and as a potential therapeutic tool, continues to …
Defining Gene Function in Spermatogonial Stem Cells Through Conditional Knockout Approaches
JMD Legrand, RM Hobbs - Spermatogonial Stem Cells: Methods and …, 2023 - Springer
Mammalian male fertility is maintained throughout life by a population of self-renewing
mitotic germ cells known as spermatogonial stem cells (SSCs). Much of our current …
mitotic germ cells known as spermatogonial stem cells (SSCs). Much of our current …
Somatic cell-derived BMPs induce male germ cell meiosis initiation during embryonic stage via regulating Dazl expression
L Zhang, Y Li, Y Hu, L Lin, J Zhou, M Chen, Y Qin… - bioRxiv, 2020 - biorxiv.org
Germ cell fate is believed to be determined by the signaling from sexually differentiated
somatic cell. However, the molecular mechanism remains elusive. In this study, ectopic …
somatic cell. However, the molecular mechanism remains elusive. In this study, ectopic …