Beyond silver sulfadiazine: A dive into more than 50 years of research and development on metal complexes of sulfonamides in medicinal inorganic chemistry

JHB Nunes, DH Nakahata, PP Corbi… - Coordination Chemistry …, 2023 - Elsevier
Sulfonamides revolutionized the treatment and management of bacterial infections. Prontosil
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …

Nimesulide silver metallodrugs, containing the mitochondriotropic, triaryl derivatives of pnictogen; anticancer activity against human breast cancer cells

CN Banti, C Papatriantafyllopoulou, M Manoli… - Inorganic …, 2016 - ACS Publications
Novel silver (I) metallo-drugs of the nonsteroidal anti-inflammatory drug nimesulide (nim)
and the mitochondriotropic triaryl derivatives of pnictogen ligands (tpE, E= P (tpp, tptp, or …

Silver complexes with sulfathiazole and sulfamethoxazole: Synthesis, spectroscopic characterization, crystal structure and antibacterial assays

JHB Nunes, REF de Paiva, A Cuin, WR Lustri, PP Corbi - Polyhedron, 2015 - Elsevier
The present work describes the synthesis and spectroscopic characterization of two silver (I)
complexes with the sulfonamides sulfathiazole (AgC 9 H 8 N 3 O 2 S 2, Ag-SFT) and …

Synthesis, characterization and in vitro biological assays of a silver (I) complex with 5-fluorouracil: A strategy to overcome multidrug resistant tumor cells

JHB Nunes, FRG Bergamini, WR Lustri… - Journal of Fluorine …, 2017 - Elsevier
A silver (I) complex with the antitumor drug 5-fluorouracil was synthesized and characterized
by a set of chemical and spectroscopic techniques. Elemental, thermogravimetric and mass …

Synthesis, crystallographic studies, high resolution mass spectrometric analyses and antibacterial assays of silver (I) complexes with sulfisoxazole and …

ATM Fiori, DH Nakahata, A Cuin, WR Lustri, PP Corbi - Polyhedron, 2017 - Elsevier
The present work describes the synthesis, structural characterization and antibacterial
assays of two silver (I) complexes with the sulfa drugs sulfisoxazole (SIZH) and …

[PDF][PDF] Characterization of nimesulide and development of immediate release tablets

HVA Rocha, R de Sousa Augusto, LD Prado… - Eclética …, 2019 - redalyc.org
This paper aims to characterize nimesulide raw materials from different manufacturers and
to develop immediate release tablets, in order to register a generic product. Also, raw …

Supramolecular Nanoassemblies Based on Proteins and Cyclodextrin Derivatives

YM Zhang, YH Liu, Y Liu - 2020 - books.rsc.org
Cyclodextrins (CDs), which were discovered fortuitously by the French scientist Antoine
Villiers in 1891 during starch fermentation experiments, are a family of truncated cone …

[PDF][PDF] ANA THEREZA FIORI DUARTE

SE SULFISOXAZOL, CEEADE PREPARAÇÃO - repositorio.unicamp.br
A descoberta dos antimicrobianos para o tratamento das mais diversas infecções
revolucionou a terapêutica que conhecemos hoje, sendo considerada um marco histórico …

Разработка технологии получения твердой дозированной лекарственной формы Грамицидина С методом влажной грануляции во взвешенном слое

ИС Ватлин - 2020 - earchive.tpu.ru
Работа посвящена исследованию процесса грануляции пептидного антибиотика с бета-
циклодекстрином во взвешенном слое. Получен и охарактеризован комплекс …

Caracterização do insumo nimesulida e desenvolvimento de uma formulação de comprimidos de liberação imediata

RS Augusto - 2015 - arca.fiocruz.br
A nimesulida é um fármaco anti-inflamatório não esteroidal (AINE), com seletividade
preferencialmente para a COX-2. A nimesulida é um ácido fraco, praticamente insolúvel em …