[HTML][HTML] Meninges: from protective membrane to stem cell niche

I Decimo, G Fumagalli, V Berton… - American journal of …, 2012 - ncbi.nlm.nih.gov
Meninges are a three tissue membrane primarily known as coverings of the brain. More in
depth studies on meningeal function and ultrastructure have recently changed the view of …

Neural stem cell niches in health and diseases

I Decimo, F Bifari, M Krampera… - Current pharmaceutical …, 2012 - ingentaconnect.com
Presence of neural stem cells in adult mammalian brains, including human, has been clearly
demonstrated by several studies. The functional significance of adult neurogenesis is slowly …

Nestin-and doublecortin-positive cells reside in adult spinal cord meninges and participate in injury-induced parenchymal reaction

I Decimo, F Bifari, FJ Rodriguez, G Malpeli, S Dolci… - Stem …, 2011 - academic.oup.com
Adult spinal cord has little regenerative potential, thus limiting patient recovery following
injury. In this study, we describe a new population of cells resident in the adult rat spinal cord …

[HTML][HTML] Classic and novel stem cell niches in brain homeostasis and repair

R Lin, L Iacovitti - Brain research, 2015 - Elsevier
Neural stem cells (NSCs) critical for the continued production of new neurons and glia are
sequestered in distinct areas of the brain called stem cell niches. Until recently, only two …

Meninges: a widespread niche of neural progenitors for the brain

I Decimo, S Dolci, G Panuccio, M Riva… - The …, 2021 - journals.sagepub.com
Emerging evidence highlights the several roles that meninges play in relevant brain
functions as they are a protective membrane for the brain, produce and release several …

Physiology of the intrathecal bolus: the leptomeningeal route for macromolecule and particle delivery to CNS

MI Papisov, VV Belov, KS Gannon - Molecular pharmaceutics, 2013 - ACS Publications
Presently, there are no effective treatments for several diseases involving the CNS, which is
protected by the blood–brain, blood–CSF, and blood–arachnoid barriers. Traversing any of …

Meninges harbor cells expressing neural precursor markers during development and adulthood

F Bifari, V Berton, A Pino, M Kusalo… - Frontiers in cellular …, 2015 - frontiersin.org
Brain and skull developments are tightly synchronized, allowing the cranial bones to
dynamically adapt to the brain shape. At the brain-skull interface, meninges produce the …

Meningeal and choroid plexus cells—Novel drug targets for CNS disorders

M Dragunow - Brain research, 2013 - Elsevier
The meninges and choroid plexus perform many functions in the developing and adult
human central nervous system (CNS) and are composed of a number of different cell types …

Existence of a potential neurogenic system in the adult human brain

AB Nogueira, MC Sogayar, A Colquhoun… - Journal of translational …, 2014 - Springer
Background Prevailingly, adult mammalian neurogenesis is thought to occur in discrete,
separate locations known as neurogenic niches that are best characterized in the …

Nestin expression as a diagnostic and prognostic marker in colorectal cancer and other tumors

A Szymańska-Chabowska… - Clinical Medicine …, 2021 - journals.sagepub.com
Lung cancer, colon cancer, breast cancer, and prostate cancer are the leading causes of
death in developed countries. Many cancers display non-specific signs in the early stage of …