Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

Effector T cells leave the lymph nodes armed with specialized functional attributes. Their
antigenic targets may be located anywhere in the body, posing the ultimate challenge: how …

Eukaryotic cells migrate by coupling the intracellular force of the actin cytoskeleton to the
environment. While force coupling is usually mediated by transmembrane adhesion …

The actin cytoskeleton drives many essential biological processes, from cell morphogenesis
to motility. Assembly of functional actin networks requires control over the speed at which …

Dendritic cells (DCs) patrol their environment by linking antigen acquisition by
macropinocytosis to cell locomotion. DC activation upon bacterial sensing inhibits …

Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

Cells navigating through complex tissues face a fundamental challenge: while multiple
protrusions explore different paths, the cell needs to avoid entanglement. How a cell surveys …

A simple method based upon masked electrospray is reported for directly generating both
unidirectional and bidirectional density gradients of biomacromolecular particles on …

Cells sense biophysical cues in the micro-environment and respond to the cues
biochemically and biophysically. Proper responses from cells are critical to maintain the …

Mechanics has been a central focus of physical biology in the past decade. In comparison,
how cells manage their size is less understood. Here, we show that a parameter central to …