[HTML][HTML] Updated diagnostic criteria and classification of mast cell disorders: a consensus proposal

P Valent, C Akin, K Hartmann, I Alvarez-Twose… - …, 2021 - journals.lww.com
Mastocytosis is a hematologic neoplasm characterized by expansion and focal
accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone …

Advances in the classification and treatment of mastocytosis: current status and outlook toward the future

P Valent, C Akin, K Hartmann, G Nilsson, A Reiter… - Cancer research, 2017 - AACR
Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the
expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The …

Diagnosis and management of anaphylaxis in precision medicine

M Castells - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
Anaphylaxis is the most severe and frightening of the allergic reactions, placing patients at
high risk and demanding prompt recognition and immediate management by health care …

Cold urticaria–What we know and what we do not know

N Maltseva, E Borzova, D Fomina, M Bizjak… - Allergy, 2021 - Wiley Online Library
Cold urticaria (ColdU) is a common form of chronic inducible urticaria characterized by the
development of wheals, angioedema or both in response to cold exposure. Recent research …

[HTML][HTML] Personalized management strategies in mast cell disorders: ECNM-AIM user's guide for daily clinical practice

P Valent, K Hartmann, J Schwaab… - The Journal of Allergy …, 2022 - Elsevier
Mastocytosis is a myeloid neoplasm defined by expansion and focal accumulation of clonal
mast cells (MCs) in one or more organs. The disease exhibits a complex pathology and may …

Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers

TW Jimenez-Rodriguez, M Garcia-Neuer… - Journal of Asthma …, 2018 - Taylor & Francis
Anaphylaxis is the most serious of all allergic reactions and can be fatal. The diagnosis is
frequently delayed, and misdiagnosis often occurs with asthma or urticaria. Biomarkers such …

KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis

M Arock, K Sotlar, C Akin, S Broesby-Olsen… - Leukemia, 2015 - nature.com
Although acquired mutations in KIT are commonly detected in various categories of
mastocytosis, the methodologies applied to detect and quantify the mutant type and allele …

The international consensus classification of mastocytosis and related entities

RJ Leguit, SA Wang, TI George, A Tzankov, A Orazi - Virchows Archiv, 2023 - Springer
Mastocytosis is a neoplasm characterized by a clonal proliferation of mast cells, which
accumulate in one or multiple organs, associated with an extremely heterogeneous clinical …

Molecular background, clinical features and management of pediatric mastocytosis: status 2021

M Lange, K Hartmann, MC Carter… - International journal of …, 2021 - mdpi.com
Pediatric mastocytosis is a heterogeneous disease characterized by accumulation of mast
cells in the skin and less frequently in other organs. Somatic or germline mutations in the KIT …

Multidisciplinary challenges in mastocytosis and how to address with personalized medicine approaches

P Valent, C Akin, KV Gleixner, WR Sperr… - International journal of …, 2019 - mdpi.com
Mastocytosis is a hematopoietic neoplasm defined by abnormal expansion and focal
accumulation of clonal tissue mast cells in various organ-systems. The disease exhibits a …