Many of the internal organ systems of Drosophila melanogaster are functionally analogous
to those in vertebrates, including humans. Although humans and flies differ greatly in terms …

FlyAtlas, a new online resource, provides the most comprehensive view yet of expression in
multiple tissues of Drosophila melanogaster. Meta-analysis of the data shows that a …

Publisher Summary This chapter discusses the insect CYP genes and P450 enzymes.
Cytochrome P450, or CYP genes, constitutes one of the largest family of genes, with …

Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila
due to rapid developments in molecular genetics approaches that overcome the difficulties …

Monosomy of the X chromosome owing to divergence between the sex chromosomes leads
to dosage compensation mechanisms to restore balanced expression between the X and …

In the last decade there have been marked reductions in malaria incidence in sub-Saharan
Africa. Sustaining these reductions will rely upon insecticides to control the mosquito malaria …

Molecular biology is reaching new depths in our understanding of the development and
physiology of Malpighian tubules. In Diptera, Malpighian tubules derive from ectodermal …

Identifying insecticide resistance mechanisms is paramount for pest insect control, as the
understandings that underpin insect control strategies must provide ways of detecting and …

Although the genetic basis of many kidney diseases is being rapidly elucidated, their
experimental study remains problematic owing to the lack of suitable models. The fruitfly …

Water is essential to life. Terrestrial insects lose water by evaporation from the body surface
and respiratory surfaces, as well as in the excretory products, posing a challenge made …