Objective Protamine 1 (PRM1) is specific in sperm and plays essential roles in fertilization,
also a member of cancer testis antigen (CTA) family. This study aims to summarize the …

Semen analysis is usually the first step in the assessment of male fertility. Although analyzes
provide valuable information about male fertility, success of cytoplasmic sperm injection …

Studies have reported the genetic gives rise to male infertility. The aim of the present meta-
analysis was to evaluate the association between PRM1 (rs737008 and rs2301365) and …

Male infertility is attributable to 60% of total infertility cases and about 30-50% of these cases
remain idiopathic. In the Middle East and North Africa region (MENA), male infertility affects …

Generation of germ cells from embryonic stem cells in vitro could have great application for
treating infertility. The temporal expression profile of several genes was expressed at …

In recent years, the incidence of teratospermia has been increasing, and it has become a
very important factor leading to male infertility. The research on the molecular mechanism of …

Objective: Almost half of infertility is related to male factors. Although the effect of genetic
factors on male infertility is identified, about 30%-50% still has no proven cause and is …

Mutations or altered expression of PRM1 gene have been associated with male infertility.
This study aimed to analyse pathogenic variations of PRM1 gene in Iranian Arab infertile …

Protamines are considered the most important structure in the sperm nucleus, and they are
proteins with a significantly large amount of amino acids carrying a positive charge, which …

Background Genetic mechanisms are associated with male infertility, but the association
with non-obstructive azoospermia (NOA) remains unclear. Mutations in the chloride channel …