Rational design of immunomodulatory hydrogels for chronic wound healing

M Kharaziha, A Baidya, N Annabi - Advanced Materials, 2021 - Wiley Online Library
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Macrophage M1/M2 polarization

C Yunna, H Mengru, W Lei, C Weidong - European journal of …, 2020 - Elsevier
Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

A 3D‐bioprinted functional module based on decellularized extracellular matrix bioink for periodontal regeneration

X Yang, Y Ma, X Wang, S Yuan, F Huo, G Yi… - Advanced …, 2023 - Wiley Online Library
Poor fiber orientation and mismatched bone–ligament interface fusion have plagued the
regeneration of periodontal defects by cell‐based scaffolds. A 3D bioprinted biomimetic …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Differential regulation of macrophage inflammatory activation by fibrin and fibrinogen

JY Hsieh, TD Smith, VS Meli, TN Tran, EL Botvinick… - Acta biomaterialia, 2017 - Elsevier
Fibrin is a major component of the provisional extracellular matrix formed during tissue
repair following injury, and enables cell infiltration and anchoring at the wound site …

Solubilized extracellular matrix bioscaffolds derived from diverse source tissues differentially influence macrophage phenotype

JL Dziki, DS Wang, C Pineda, BM Sicari… - … research Part A, 2017 - Wiley Online Library
The host response to biomaterials is a critical determinant of their success or failure in tissue‐
repair applications. Macrophages are among the first responders in the host response to …

Extracellular matrix‐based strategies for immunomodulatory biomaterials engineering

AT Rowley, RR Nagalla, SW Wang… - Advanced healthcare …, 2019 - Wiley Online Library
The extracellular matrix (ECM) is a complex and dynamic structural scaffold for cells within
tissues and plays an important role in regulating cell function. Recently it has become …