Combining in vitro and in silico approaches to find new candidate drugs targeting the pathological proteins related to the Alzheimer's disease

H Li, X Wang, H Yu, J Zhu, H Jin… - Current …, 2018 - ingentaconnect.com
Background: Alzheimer's disease (AD) as the most common cause of dementia among older
people has aroused the universal concern of the whole world. However, until now there is …

Current Therapy and Computational Drug Designing Approaches for Neurodegenerative Diseases-with Focus on Alzheimer's and Parkinson's.

I Bera - Current Signal Transduction Therapy, 2019 - ingentaconnect.com
Background: Neurodegenerative diseases are age-related ailments which are characterized
by progressive neuronal damage and loss. These diseases can be caused by both genetic …

Design of Amphiphilic Macromolecule and Antioxidant Based Nanotherapeutics for Microglia-Mediated Neuroinflammation in Synucleinopathy

N Zhao - 2022 - search.proquest.com
As one of the main types of synucleinopathies, Parkinson's disease (PD) is a progressive
neurodegenerative disorder, characterized by the accumulation and aggregation of alpha …

Određivanje strukture farmakofore, dizajn i in vitro ispitivanje liganada sa višestrukim dejstvom kao potencijalno efikasnijih terapeutika složenih neuroloških i …

MM Radan - 2022 - search.proquest.com
Disfunkcija serotoninske i dopaminske neurotransmisije u mozgu je u osnovi patofiziologije
brojnih neuroloških i mentalnih oboljenja. Definisanje protokola koji integriše in silico i in …