A staphylococcal capsule-producing enzyme that unfolds via multiple intermediates predominantly exists as the trimers at low concentrations

T Chakraborty, S Polley, N Ray Chaudhuri… - Journal of …, 2024 - Taylor & Francis
CapG, an enzyme expressed by Staphylococcus aureus, catalyzes an epimerization
reaction to synthesize N-acetyl-L-fucosamine, a constituent of capsule involved in …

Modeling and monitoring the effects of three partly conserved Ile residues in the dimerization domain of a Mip-like virulence factor from Escherichia coli

S Seal, T Chakraborty, S Polley, D Paul… - Journal of …, 2024 - Taylor & Francis
FKBP22, an Escherichia coli-made peptidyl-prolyl cis-trans isomerase, has shown
considerable homology with Mip-like virulence factors. While the C-terminal domain of this …

Serine 106 preserves the tertiary structure, function, and stability of a cyclophilin from Staphylococcus aureus

S Seal, N Banerjee, R Mahato, T Kundu… - Journal of …, 2023 - Taylor & Francis
SaCyp, a staphylococcal cyclophilin involved in both protein folding and pathogenesis, has
a Ser residue at position 106 and a Trp residue at position 136. While Ser 106 of SaCyp …

Structurally distinct unfolding intermediates formed from a staphylococcal capsule-producing enzyme retained NADPH binding activity

T Chakraborty, S Polley, D Sinha, S Seal… - Journal of …, 2022 - Taylor & Francis
CapF, a capsule-producing enzyme expressed by Staphylococcus aureus, binds NADPH
and exists as a dimer in the aqueous solution. Many other capsule-producing virulent …

The cofactors and domains of a staphylococcal capsule-producing enzyme preserve its structure, stability, shape and dimerization ability

T Chakraborty, N Banerjee, D Sinha… - The Journal of …, 2023 - academic.oup.com
CapF, a staphylococcal capsule-producing enzyme, binds Zn2+ ion and NADPH using its C-
terminal domain (CTD) and N-terminal domain (NTD), respectively. To elucidate the roles of …