Endocannabinoid system components as potential biomarkers in psychiatry

F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2020 - frontiersin.org
The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision.
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …

Cannabis and psychosis: a critical overview of the relationship

C Ksir, CL Hart - Current psychiatry reports, 2016 - Springer
Interest in the relationship between cannabis use and psychosis has increased dramatically
in recent years, in part because of concerns related to the growing availability of cannabis …

The endocannabinoid system in mental disorders: Evidence from human brain studies

I Ibarra-Lecue, F Pilar-Cuéllar, C Muguruza… - Biochemical …, 2018 - Elsevier
Mental disorders have a high prevalence compared with many other health conditions and
are the leading cause of disability worldwide. Several studies performed in the last years …

Molecular alterations of the endocannabinoid system in psychiatric disorders

D Navarro, A Gasparyan, F Navarrete… - International journal of …, 2022 - mdpi.com
The therapeutic benefits of the current medications for patients with psychiatric disorders
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …

Cannabinoid receptor gene CNR1 is downregulated in subcortical brain samples and upregulated in blood samples of individuals with schizophrenia: A participant …

S Bloch Priel, A Yitzhaky, D Gurwitz… - European Journal of …, 2023 - Wiley Online Library
Cannabis use leads to symptom exacerbation in schizophrenia patients, and
endocannabinoid ligands have been studied as tentative schizophrenia therapeutics. Here …

Bridging the gap between genes and language deficits in schizophrenia: an oscillopathic approach

E Murphy, A Benítez-Burraco - Frontiers in Human Neuroscience, 2016 - frontiersin.org
Schizophrenia is characterized by marked language deficits, but it is not clear how these
deficits arise from the alteration of genes related to the disease. The goal of this paper is to …

Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies

V Reddy, D Grogan, M Ahluwalia, ÉL Salles… - EPMA Journal, 2020 - Springer
Cannabis-inspired medical products are garnering increasing attention from the scientific
community, general public, and health policy makers. A plethora of scientific literature …

Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls

R Ferretjans, RP de Souza, B Panizzutti… - Brazilian Journal of …, 2021 - SciELO Brasil
Objective: To test the hypothesis that genetic variations of cannabinoid receptors contribute
to the pathophysiology of cognitive deficits in schizophrenia. Methods: In this genetic …

Toward the language oscillogenome

E Murphy, A Benítez-Burraco - Frontiers in psychology, 2018 - frontiersin.org
Language has been argued to arise, both ontogenetically and phylogenetically, from
specific patterns of brain wiring. We argue that it can further be shown that core features of …

Association of a Variant of CNR1 Gene Encoding Cannabinoid Receptor 1 With Gilles de la Tourette Syndrome

N Szejko, JP Fichna, K Safranow, T Dziuba… - Frontiers in …, 2020 - frontiersin.org
Background Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder of unknown
etiology, although a major role of genetic factors has been established. Cannabis-based …