Role of Hedgehog and Hippo signaling pathways in cancer: a special focus on non-coding RNAs

U Sharma, HS Tuli, V Uttam, R Choudhary… - Pharmacological …, 2022 - Elsevier
Despite advanced clinical and translational oncology research, mortality rates are still
increasing worldwide. Recently, a class of non-coding RNAs (ncRNAs), such as microRNAs …

Various LncRNA mechanisms in gene regulation involving miRNAs or RNA-binding proteins in non-small-cell lung cancer: main signaling pathways and networks

EA Braga, MV Fridman, AM Burdennyy… - International Journal of …, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) are crucial players in the pathogenesis of non-small-cell
lung cancer (NSCLC). A competing binding of lncRNAs and mRNAs with microRNAs …

Neutrophil extracellular traps (NETs)-related lncRNAs signature for predicting prognosis and the immune microenvironment in breast cancer

T Jiang, Y Wang, X Chen, W Xia, S Xue… - Frontiers in Cell and …, 2023 - frontiersin.org
Background: Neutrophil extracellular traps (NETs) are closely associated to tumorigenesis
and development. However, the relationship between NETs-related long non-coding RNAs …

YAP/TAZ: Molecular pathway and disease therapy

Y Wei, VLZ Hui, Y Chen, R Han, X Han, Y Guo - MedComm, 2023 - Wiley Online Library
The Yes‐associated protein and its transcriptional coactivator with PDZ‐binding motif
(YAP/TAZ) are two homologous transcriptional coactivators that lie at the center of a key …

The interplay between noncoding RNA and YAP/TAZ signaling in cancers: molecular functions and mechanisms

Y Zhang, Y Wang, H Ji, J Ding, K Wang - Journal of Experimental & …, 2022 - Springer
The Hippo signaling pathway was found coordinately modulates cell regeneration and
organ size. Its dysregulation contributes to uncontrolled cell proliferation and malignant …

Deciphering the role of Hippo pathway in lung cancer

S Ghafouri-Fard, Y Poornajaf, BM Hussen… - … -Research and Practice, 2023 - Elsevier
Hippo pathway has been initially recognized as a regulatory mechanism for modulation of
organ size in fruitfly. Subsequently, its involvement in the regulation of homeostasis and …

Integrated plasma and exosome long noncoding RNA profiling is promising for diagnosing non-small cell lung cancer

N Wang, C Yao, C Luo, S Liu, L Wu, W Hu… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Non-small cell lung cancer (NSCLC) accounts for more than 80% of all lung
cancers, and its 5-year survival rate can be greatly improved by early diagnosis. However …

[HTML][HTML] Crosstalk between lncRNAs and Wnt/β-catenin signaling pathways in lung cancers: From cancer progression to therapeutic response

T Wu, YR Dong, XZ Yang, L Mo, Y You - Non-coding RNA Research, 2024 - Elsevier
Lung cancer (LC) is considered to have the highest mortality rate around the world. Because
there are no early diagnostic signs or efficient clinical alternatives, distal metastasis and …

Hippo-YAP/TAZ pathway regulation: the crucial roles of lncRNAs in cancer

W Jang, M Im, J Roh, JH Kang, W Kim - Animal Cells and Systems, 2023 - Taylor & Francis
The Hippo signaling pathway is a conserved signaling pathway that regulates cell
proliferation, apoptosis, and differentiation and plays essential roles in the maintenance of …

Molecular mechanism of Curcumin Derivative on YAP pathway against Ovarian Cancer

N Zheng, S Liu, H Zeng, H Zhao, L Jin - Journal of Clinical Medicine, 2022 - mdpi.com
The purpose of this study is to study the effect of curcumin derivative WZ10 on the
proliferation, invasion and apoptosis of ovarian cancer OVCAR3 cells, and to explore its …